Protein Info for Rru_A2113 in Rhodospirillum rubrum S1H

Annotation: Serine-type D-Ala-D-Ala carboxypeptidase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details PF00768: Peptidase_S11" amino acids 48 to 266 (219 residues), 184.5 bits, see alignment E=3.6e-58 PF13354: Beta-lactamase2" amino acids 52 to 198 (147 residues), 41.3 bits, see alignment E=1.8e-14 PF05036: SPOR" amino acids 384 to 464 (81 residues), 34.3 bits, see alignment E=3.7e-12

Best Hits

KEGG orthology group: K01286, D-alanyl-D-alanine carboxypeptidase [EC: 3.4.16.4] (inferred from 100% identity to rru:Rru_A2113)

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4

Use Curated BLAST to search for 3.4.16.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSI2 at UniProt or InterPro

Protein Sequence (468 amino acids)

>Rru_A2113 Serine-type D-Ala-D-Ala carboxypeptidase (NCBI) (Rhodospirillum rubrum S1H)
MNHLPELPSSGRAGSGATEPAAGRLRILAMLAVVFLLLGLPTQAFAGYASIVVDASTGRV
LQARNADMRNYPASLTKMMTLYLLFEAIDNGKYTLESRLPVSKWAANQAPSKLGVAAGTG
IKVEHAIKALVTKSANDVAVVIAEALGGTEANFSALMTRKAAALGMSQTTFRNASGLPNN
GQMTTARDMAVLSMALIRHFPNHYRFFATQSFRFGNRTITTHNHVVREYPGADGLKTGYI
QASGFNVASSAVRNGRRLVAVVFGGQTARARDTQMMALLDEGFATLAREGGSVVQAKRKP
DAIASIIKAKEPPAADMGSADDAPMPPAYKPGSLTASVSGGRTQQMALATPMRSSPAPSA
KSAPGPRPTPIARTTPVPSKGAAKGDWGIQVGAYAKSAAATAAANKAIGLLAAEARRQVS
PVVVQRKSGSGTIYRARLTGLSNEAAARTACATLVRNDHSCLVVAPQK