Protein Info for Rru_A2108 in Rhodospirillum rubrum S1H

Annotation: Multi-sensor Hybrid Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 924 transmembrane" amino acids 18 to 39 (22 residues), see Phobius details amino acids 263 to 280 (18 residues), see Phobius details amino acids 286 to 306 (21 residues), see Phobius details PF13188: PAS_8" amino acids 334 to 387 (54 residues), 26.4 bits, see alignment 1.2e-09 PF00512: HisKA" amino acids 402 to 465 (64 residues), 70.1 bits, see alignment 3.3e-23 PF02518: HATPase_c" amino acids 512 to 627 (116 residues), 98.2 bits, see alignment E=9.8e-32 PF00072: Response_reg" amino acids 658 to 772 (115 residues), 87.6 bits, see alignment E=1.7e-28 PF01627: Hpt" amino acids 831 to 901 (71 residues), 31.6 bits, see alignment 4e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2108)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSI7 at UniProt or InterPro

Protein Sequence (924 amino acids)

>Rru_A2108 Multi-sensor Hybrid Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MNRDRLPTFLSDGASRGVLASGVAFGLIITLLVGFWGWISYRDSLARAASVTEGYTLTYK
AFSEQVFGRIAGVVDEVDHRFESSADDQAKLGHYVREQAILFPVLSDVVILDARGRVRLA
GKAPPRLTDRVFPMADRLLGGRDEPGMVVTPLFRSDTDGGPWVFAVGRTLVGADGTVAGA
VAAVIDQKRFNDSFAVLLENDMATVVLALADGKILARAPEAGFHPGAALLSVAERQGVVV
ERRSGITRSSLDGVMRIFNERRLSGYPLLVIGTIAKSAALSDWSGWMVLGGLLVATVLIA
DGWVTIQLMRQLGRRRTAEARLSLQNAVLTSQRETSPDGILVADLSWRLISWNQRFLDIW
RVSDDLMRQADGRTLLTQIEPLLEDAPVFRADVVDQMTQAASQFLAVMSHEIRTPMTGIL
GMGDLLLTSGLNEEQEKYGRTLMRSARTLLGLLDDVLDFSKIEAGQLELEVVDFSPVEVL
QDVIGLFLPKASERGLVLSSRLPEGPPPILRGDPTRLRQVLFNLVGNAVKFTARGGVEVR
MDVGEAVGDQIPLTLSIIDSGVGMDARQRARLFNPFTQADVSTTRRFGGTGLGLTICKRL
VEMMGGTIEIDSTLGEGSTFRVRVTLTRGDASKVVSLEGHGLGHPLDLPGPRPAGRRILL
VEDNDTNRLLIATVLERSGHNVDTAADGRQGVDAVSAATEPYDLILMDMQMPEMDGPDAT
RAIRALSGPAAHTPIVALTADVRAEDRDRYLASGLDDLLTKPVDWTRLREVIERLTGPGQ
TRPQVRPGGDEVLKRAAWEEEPAFDGSVLASLAEQLGTNRLRPLITSAMANLSRHFDLLE
KTMANGSAQDVRRSAHALKGMAGQFGARRAQALSLAIEEEADRPQAARALLPFLRIAIEG
ARGGLEALVDPTTAPGEKRGREAR