Protein Info for Rru_A2094 in Rhodospirillum rubrum S1H

Annotation: Acriflavin resistance protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1037 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 333 to 352 (20 residues), see Phobius details amino acids 359 to 381 (23 residues), see Phobius details amino acids 387 to 409 (23 residues), see Phobius details amino acids 430 to 450 (21 residues), see Phobius details amino acids 462 to 489 (28 residues), see Phobius details amino acids 519 to 542 (24 residues), see Phobius details amino acids 850 to 868 (19 residues), see Phobius details amino acids 878 to 898 (21 residues), see Phobius details amino acids 904 to 928 (25 residues), see Phobius details amino acids 949 to 969 (21 residues), see Phobius details amino acids 981 to 1004 (24 residues), see Phobius details PF00873: ACR_tran" amino acids 4 to 1007 (1004 residues), 989.8 bits, see alignment E=1.4e-301 PF03176: MMPL" amino acids 296 to 486 (191 residues), 31.6 bits, see alignment E=9e-12

Best Hits

KEGG orthology group: K03296, hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family (inferred from 100% identity to rru:Rru_A2094)

Predicted SEED Role

"RND multidrug efflux transporter; Acriflavin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSK1 at UniProt or InterPro

Protein Sequence (1037 amino acids)

>Rru_A2094 Acriflavin resistance protein (NCBI) (Rhodospirillum rubrum S1H)
MDVSSLFIRRPVFATVLSLLLVVMGIAAMTRLAVRELPDIDSAVVSVTTPYTGAAPEIVD
TDITEVIENAVAGVSGIRTITSQSRRGQGRTVIEFESGVSMDEAVNDVRDAVAKVRGDLP
DDIEEPRIAKSDTDSDPVMRLSLTSPRMTPIELTDFADRYIVDRLATIDGVAQVDLYGER
RQAIRLWLDRRAMAARQVTVQDVEAALRRANVELPAGEIESASRLLTVRAATLLTSPEAF
GSTVIKVVDGYPLRVRDVARVELGVENDDTTVRVEGRDALTMGVLRQSQANTVAISNRIR
AEIDRLRPSLPEGMSLEVSSDDALFINRSIHEVILTLGLSGLIVIIVNFAFLGSIRATLV
PTVTIPVAVIGTFIGILLLGFSINLLTLLALILSIGLVVDDAIVVLENIQRRIEAGEPKL
VAAARGTRQVTFAVVATSLTLIAVFVPISFMEGTVGRLFTEFGFVLACAVAISMLVALTL
CPPLAAGVLAEGKAEGRLAHALNYAFGTLSRGYQRALSAVLGLPMVVLTVALLCGGASFW
LYQGLPKELVPVEDRGVVVVSLNGPQGANTRYTDTQIRAVEAAVQPVLDRGEAVGVLAQV
GQWNRPHRGYVVIRLDDWENRGRTASALAESLRKDLGKLAGATATPVVPAGLGLRGSRTP
LQVVIGGPDYAEVEVWANALLKRAEELPGLINPELDFEQNQPQLSVGIDRDRADDLGVGV
EAIGQTLQTMLASREVTRFVDRGREYQVVVQARPEDRRTPSDLSNTFVRAEKGGALVPLD
ALVILKETAGAPDLNRYARLPSITLQSALAPGYDMGQAIDDVMALASQTVPPEARLSLAG
QSKEFLETSGGVLFTFLMALVIVYLVLAAQFESFLHPLIIMLSVPLAVSGALLSLWATGN
SINVYSQIGIVLLIGLTAKNGILIVEFANQLRDEGRSVREAILEAASLRLRPILMTVICT
ILGAVPLAWSSGAGAESREAIGIVVIGGLGLASLLTLFVTPVLYDLLAPFTRSAGAVGQA
LDRALAETPEGAGKPAE