Protein Info for Rru_A2065 in Rhodospirillum rubrum S1H

Annotation: Proline racemase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF05544: Pro_racemase
  • amino acids 8 to 330 (323 residues), 428 bits, E=1.2e-132

Best Hits

Swiss-Prot: 65% identical to 4HYPE_BRUC2: 4-hydroxyproline epimerase (BCAN_A1830) from Brucella canis (strain ATCC 23365 / NCTC 10854)

KEGG orthology group: K12658, 4-hydroxyproline epimerase [EC: 5.1.1.8] (inferred from 100% identity to rru:Rru_A2065)

Predicted SEED Role

"4-hydroxyproline epimerase (EC 5.1.1.8)" in subsystem Proline, 4-hydroxyproline uptake and utilization (EC 5.1.1.8)

MetaCyc Pathways

• trans-4-hydroxy-L-proline degradation II (2/4 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.1.8

Sequence Analysis Tools

See Q2RSN0 at UniProt or InterPro

Protein Sequence (333 amino acids)

>Rru_A2065 Proline racemase (NCBI) (Rhodospirillum rubrum S1H)
MARHTFSCIDAHTCGNPVRLVSGGAPLLTGATMMERRAHFLREYDWIRTGLMFEPRGHDA
MSGSILYPPTRADCDIAILFIETSGCLPMCGHGTIGTVTVALEHGLVRPREPGLLRLDTP
AGVVEARYTQQGDKITSVRLRNVPAYLHGTGYQVEVPGLGPLTFDIAYGGNFYAIIEPQP
GYADLDALSVMDIQSFSPKIRALVNERYEIIHKADPRLRGLSHVMWTGKPRDALAQGRNA
VFYGERGVDRSPCGTGTSARMAQLAARGALAPGDAFVHESIIGSLFHGRVEEATTVGDSP
AIIPSVEGSAWVTGLNTLFLYDEEPYSQGFLLP