Protein Info for Rru_A2058 in Rhodospirillum rubrum S1H

Annotation: Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 transmembrane" amino acids 25 to 44 (20 residues), see Phobius details amino acids 205 to 225 (21 residues), see Phobius details PF13675: PilJ" amino acids 50 to 151 (102 residues), 32 bits, see alignment E=1.7e-11 PF00512: HisKA" amino acids 274 to 339 (66 residues), 39.4 bits, see alignment E=7.8e-14 PF02518: HATPase_c" amino acids 384 to 492 (109 residues), 83.4 bits, see alignment E=2.4e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2058)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSN7 at UniProt or InterPro

Protein Sequence (499 amino acids)

>Rru_A2058 Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MNGAQKDEKADLPKSRPVAGWMTRRYLLALSLIALLALSGYLTFDKLAAQHDRTLGLVNI
SGRQRMLSQRTALYAERLVRDDCPEPVDVCHRILGEATDLLEDSHRALTRGSAEMGLPVA
KSPEIRALYFDGAPSLDQRMTDYLAALRQILTATRAGDDTLALDAYRRVVRESSGPLLDD
LDRLVARHQSEGEAALEHLDRAESAILALTLLTLLLEIVLIFRPMVTQIHRQFAALDHMT
AALRRSRDGLEDIVEQRTADIDRARAEAVKASHSKSRFLAAAGHDLMQPLEGAMMYAGAL
GRQAETDRARQAVAELKNAHQAMSRLIRSILEISKLDCGAVEPLPRVFALGPLLDQLVGE
VQPQAQAKGLRVRRVWTSARLETDPLLLERILRNLLANALRHTHKGGIVLGVRRRADGLD
IAVADSGIGIAAQNLGRIFEAFIQIDGGQLDRSEGLGLGLAIVDRLSRLLGLDVSVRSRL
GKGTVFSLHIPSGALADDR