Protein Info for Rru_A2010 in Rhodospirillum rubrum S1H

Annotation: Aminotransferase, class V (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 PF00266: Aminotran_5" amino acids 98 to 312 (215 residues), 69.2 bits, see alignment E=1.7e-23

Best Hits

Swiss-Prot: 58% identical to PPAT_RHILO: Pyridoxamine--pyruvate transaminase (ppaT) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2010)

MetaCyc: 58% identical to pyridoxamine-pyruvate aminotransferase subunit (Mesorhizobium loti)
Pyridoxamine--pyruvate transaminase. [EC: 2.6.1.30]

Predicted SEED Role

"Pyridoxamine-pyruvate aminotransferase (EC 2.6.1.30)" (EC 2.6.1.30)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RST5 at UniProt or InterPro

Protein Sequence (388 amino acids)

>Rru_A2010 Aminotransferase, class V (NCBI) (Rhodospirillum rubrum S1H)
MAPPSPPLMLTTGPVTAYPEVSEALSRPILYDGDDAFRGYYAQVLAMLGRVMGLSTPPVI
LQGEAILGIEAAAAGLIGPKDVVLNLVSGVYGQGFGRYALRAGAEVIELAVPFDAAIDPA
DVARSLRARPDIGVVAVCHHDTPSGTLNPLADIGAVVAAHGALLIVDAVSSFGGMEVFPE
AVAADLFITSPAKCLGGTPGLSLLGVSDRAWAKMRANPQAPRGSFLSLLDWQDVIEDGRT
FPVTPSIAEIYGLEAALARHLAEGERAVWARHALTARATRAGILALGLALWPTSEALCSP
TTTAIRIPDGLSDKALRDHARDRSGVLLSLGRGATAGKVLRIGHMGPAAQPDHALRAVAA
LAAAASAQGLAVDRPAGESAVRAVIDGM