Protein Info for Rru_A2003 in Rhodospirillum rubrum S1H

Annotation: Radical SAM (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 707 TIGR03904: uncharacterized radical SAM protein YgiQ" amino acids 23 to 606 (584 residues), 848.5 bits, see alignment E=1.2e-259 PF08497: Radical_SAM_N" amino acids 23 to 341 (319 residues), 447.6 bits, see alignment E=3.2e-138 PF04055: Radical_SAM" amino acids 342 to 547 (206 residues), 35.3 bits, see alignment E=2e-12 PF11842: DUF3362" amino acids 556 to 664 (109 residues), 152.6 bits, see alignment E=1.4e-48

Best Hits

Swiss-Prot: 71% identical to Y679_RHOPA: UPF0313 protein RPA0679 (RPA0679) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2003)

Predicted SEED Role

"Fe-S OXIDOREDUCTASE (1.8.-.-)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSU2 at UniProt or InterPro

Protein Sequence (707 amino acids)

>Rru_A2003 Radical SAM (NCBI) (Rhodospirillum rubrum S1H)
MEAAKSLFSYKPFWAKRLGTAPFLPMSRAEMDALGWDACDIIVVTGDAYVDHASFGMAVI
GRVLEAQGFRVGIISQPDWTSADPFRALGRPTLFFGVTAGNMDSMVNRYTSDRKIRKDDA
YTPGAEGGRRPDRAVTVYSQRCREAFRDVPIVLGGIEASLRRVAHYDYWSDKVRRSVMLD
SKADILLFGNAERALIELAHRLAKGEAISTIRDLRGTAYMLPRVPEGWAVLDASDVDADS
GAMPRGPLGVPAVIRLPSYEVVRDDPVQYTHASRVGHLESNPGHARPLVQAHGDREVWLN
PPPLPLETGEMDRVFELPYARAPHPSYGGARIPAWEMIRFSVNVMRGCFGGCSFCSITEH
EGKVIQSRSEGSILREIEQIRDKTEGFTGVVSDLGGPTANMWRLNCSDPKIQAVCRRWSC
VYPDICKNLETDQTPLVDLYRKARAIQGVKKITIASGLRYDLAVKTPAYVKELVTHHVGG
YLKIAPEHTEDGPLALMMKPGMGAYDRFRALFETFSKQAGKQQFLIPYFIAAHPGTTDED
MMNLALWLKRNHFRADQVQTFLPSPMSLATAMYHGERNPLKPVRRDGPVVATAKGLRQRR
LHKAFLRYHDPENWPMLREALRQMGRTDLIGMSKKHLIPGHQPTGTGLAGGEGARAGRKN
GAQTFLTQQTRQGQGPYDPTRGAPSCPRDAAPGAKPGRGRPRRSTGR