Protein Info for Rru_A1853 in Rhodospirillum rubrum S1H

Annotation: Peptidase S26A, signal peptidase I (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 245 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 36 to 56 (21 residues), see Phobius details PF10502: Peptidase_S26" amino acids 11 to 217 (207 residues), 181.3 bits, see alignment E=7.4e-58 TIGR02227: signal peptidase I" amino acids 13 to 219 (207 residues), 167.8 bits, see alignment E=8.7e-54

Best Hits

KEGG orthology group: K03100, signal peptidase I [EC: 3.4.21.89] (inferred from 100% identity to rru:Rru_A1853)

Predicted SEED Role

"Signal peptidase I (EC 3.4.21.89)" in subsystem Signal peptidase (EC 3.4.21.89)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.89

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RT92 at UniProt or InterPro

Protein Sequence (245 amino acids)

>Rru_A1853 Peptidase S26A, signal peptidase I (NCBI) (Rhodospirillum rubrum S1H)
MSRKKGGGLGETIKTVVYAFLIAIVIRTFAYEPFRIPSGSMIPTLLVGDYLFVSKFSYGY
SRFSFPMGIIPFSGRVLGDVPKRGDVVVFKEPNDTSVDFIKRVVGLPGDRIQVIDGILNV
NGEPVRRERTEDFVQREAGGSVLRLTQYQETLPNGVVHPILEIHGDTYFLDNTREFRVPE
GHYFMMGDNRDSSQDSRATVGFVPAENLVGRAEFVFFSHDGSAAIWQVWKWPFAIRWDRF
FHSID