Protein Info for Rru_A1805 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 886 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details PF13188: PAS_8" amino acids 47 to 99 (53 residues), 22.5 bits, see alignment 2.9e-08 amino acids 322 to 364 (43 residues), 21.8 bits, see alignment 4.8e-08 PF00989: PAS" amino acids 50 to 101 (52 residues), 27.1 bits, see alignment 1.2e-09 amino acids 323 to 426 (104 residues), 31.2 bits, see alignment E=7e-11 PF08448: PAS_4" amino acids 51 to 94 (44 residues), 25.2 bits, see alignment 5.7e-09 amino acids 331 to 434 (104 residues), 42 bits, see alignment E=3.3e-14 PF13426: PAS_9" amino acids 53 to 91 (39 residues), 13.8 bits, see alignment (E = 2.1e-05) amino acids 330 to 431 (102 residues), 47.5 bits, see alignment E=6.7e-16 PF13185: GAF_2" amino acids 173 to 309 (137 residues), 30.7 bits, see alignment E=1.2e-10 TIGR00229: PAS domain S-box protein" amino acids 325 to 439 (115 residues), 48 bits, see alignment E=1.3e-16 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 443 to 601 (159 residues), 121.6 bits, see alignment E=2.8e-39 PF00990: GGDEF" amino acids 445 to 599 (155 residues), 152.7 bits, see alignment E=2.6e-48 PF00563: EAL" amino acids 621 to 856 (236 residues), 235.5 bits, see alignment E=2e-73

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A1805)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTE0 at UniProt or InterPro

Protein Sequence (886 amino acids)

>Rru_A1805 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI) (Rhodospirillum rubrum S1H)
MTFEDPSFWAALLTAATTAGAITILVALVRRNQAKGPDRRAREDAEIFLGLSDGLIVLDD
GGRVSALNRAAQRMTGQEGEAAVGKSARRLLPGLESVLEGKDRLASSLGLWCRLPATGRE
EALASTLGALLSETTGPAGTRTVLVLRDISEQIRLTEVDDWLRVIDGHLLAGTSLGDLAN
DLCERVARAFGLPLLWIGVPRPEGLLVVGKGGSEAARLSAYPEGRGDEGTQGVAGRTLRS
GRAQSDDAGEGWAAPTWAPGVPLGRAYCVGLRARGEVVAVLCLRGHGEAPSPALSRALEA
LGPRLGEAIVYERGQSLMRLQSAAIAAAANAIVITDGEGRVEWVNEAYHLLSGYERDQII
GTLPAVLAGPSAANPTAIEAWPTLRAGQVWRGEIHETHRDGRTYIVDKTITPIVDASGRL
SHLVAVDEDVTARKKAEERIRYLSNYDTLTRLPNRVLFRDRLYQAVVQARRGHGGLAVMF
IDLDQFSLVNDTLGHAAGDHLLMTIASRINAAAEEADTVARVGGDEFALIQTALTSADSA
ASLARRLIDVIRTPVDLGGREVVIGANVGIAIYPQDGTDPDNLMKNADMAMYRAVKSGDD
SCCFFSNEMNAEAAVRLSLEEDLRRALDSGDQLFLHYQLQFCIESGRPVGAEALARWTHP
TLGAIPPTRFIPVAEDSGLILALGDWVLGTALAEYARWRAAGCGRLTIAVNMSAVQFRQK
GLVERVTDLLAQHGVPPEDLELELTESMLMQDADQAVAQLTALSQAGIRLSIDDFGTGYS
SLGYLKLFRVDKLKVDQSFVRDVTEDGNDAVIARAIINLGHSLGLEVIAEGVETPEQMAY
LRREGCDVVQGYLMAYPEPGETVARRLLALDALSAAPAAVVMSRSD