Protein Info for Rru_A1790 in Rhodospirillum rubrum S1H

Annotation: ABC-2 transporter component (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 transmembrane" amino acids 26 to 44 (19 residues), see Phobius details amino acids 176 to 200 (25 residues), see Phobius details amino acids 227 to 248 (22 residues), see Phobius details amino acids 257 to 280 (24 residues), see Phobius details amino acids 287 to 308 (22 residues), see Phobius details amino acids 344 to 366 (23 residues), see Phobius details PF12698: ABC2_membrane_3" amino acids 33 to 364 (332 residues), 129.4 bits, see alignment E=2.7e-41 PF12679: ABC2_membrane_2" amino acids 127 to 369 (243 residues), 56.5 bits, see alignment E=4e-19 PF01061: ABC2_membrane" amino acids 171 to 332 (162 residues), 103.4 bits, see alignment E=1.9e-33

Best Hits

Swiss-Prot: 43% identical to YBHR_ECO57: Probable multidrug ABC transporter permease YbhR (ybhR) from Escherichia coli O157:H7

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 100% identity to rru:Rru_A1790)

MetaCyc: 43% identical to ABC exporter membrane subunit YbhR (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-366 [EC: 7.6.2.2]

Predicted SEED Role

"ABC transport system, permease component YbhR"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTF5 at UniProt or InterPro

Protein Sequence (371 amino acids)

>Rru_A1790 ABC-2 transporter component (NCBI) (Rhodospirillum rubrum S1H)
MGGGTRLKALIVKEFLAILRDPKGRMILIVPPLLQLFVFSYATTLEVKNADIILLNRDSG
GWGWELVQRLDGTPTIGRILITGDPAQVRAAIDGQRVLAAVEIGPAFSRDIEAGRPATVQ
ILLDGRRSNAAQIVAGYLNQIVADLAAETPRGRRTEAKAPTVIARSWFNPNLLSQWAMVP
GLVAIIALLTGLVVTALSIAREREFGTFDQLMVSPLRTHEILAGKMIPPILIGLAHITAF
LVVSIFVFEIPFRGSLFVLYGSSVVYLAAVVGLGLFISALSMTQQQAILGAFMLMVPMVL
LSGFASPIDNMPEWLQPLTRLDPLRYYLVIVKGLFLKDLALTEVIANVVPLAAIAVVTLG
AAAWLFRRRME