Protein Info for Rru_A1743 in Rhodospirillum rubrum S1H

Annotation: Coenzyme A biosynthesis protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 172 TIGR01510: pantetheine-phosphate adenylyltransferase" amino acids 7 to 164 (158 residues), 186.2 bits, see alignment E=3.9e-59 TIGR00125: cytidyltransferase-like domain" amino acids 7 to 63 (57 residues), 69.1 bits, see alignment E=2.9e-23 PF01467: CTP_transf_like" amino acids 9 to 141 (133 residues), 86 bits, see alignment E=1.4e-28

Best Hits

Swiss-Prot: 100% identical to COAD_RHORT: Phosphopantetheine adenylyltransferase (coaD) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K00954, pantetheine-phosphate adenylyltransferase [EC: 2.7.7.3] (inferred from 100% identity to rru:Rru_A1743)

Predicted SEED Role

"Phosphopantetheine adenylyltransferase (EC 2.7.7.3)" in subsystem Coenzyme A Biosynthesis (EC 2.7.7.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTK2 at UniProt or InterPro

Protein Sequence (172 amino acids)

>Rru_A1743 Coenzyme A biosynthesis protein (NCBI) (Rhodospirillum rubrum S1H)
MMPTERIAVYPGTFDPVTNGHLDIISRAARLVDRLTVGVAVNAGKGPLFSLEERVEMVRV
AVDKLPTNGATITVVPFANLLMDFACAQGASMIFRGLRAISDFEYEFQMCGMNSRLNSKV
ETVFLMASERSQFISSRFVKEIGRLGGDIGGFVPAHVRDRLLDRFEEDAESA