Protein Info for Rru_A1676 in Rhodospirillum rubrum S1H

Annotation: Dihydrouridine synthase TIM-barrel protein nifR3 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 TIGR00737: putative TIM-barrel protein, nifR3 family" amino acids 14 to 325 (312 residues), 336.9 bits, see alignment E=6.1e-105 PF01207: Dus" amino acids 15 to 323 (309 residues), 316.6 bits, see alignment E=8.1e-99

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A1676)

Predicted SEED Role

"tRNA dihydrouridine synthase B (EC 1.-.-.-)" (EC 1.-.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.-.-.-

Use Curated BLAST to search for 1.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTR9 at UniProt or InterPro

Protein Sequence (362 amino acids)

>Rru_A1676 Dihydrouridine synthase TIM-barrel protein nifR3 (NCBI) (Rhodospirillum rubrum S1H)
MTPSPAFPVSDPLIMLAPMAGVTDSPFRRLAHDYGCPLSWTEMVASRELLRERARGVDPR
LGGGAEAGRAGPFAVQLAGCDPLIMAEAARRVEGAGAELIDINMGCPVRKVVGGLGGSAL
MRDLPLAARILEAVVGAVTLPVSLKMRLGWDDASRNAVELARLAESAGISRLTVHGRTRA
QMYDGRADWPAIGLVKRAVSLPVIANGDVTNLSEAREILAVTGADGVMIGRAALGAPWLP
GAIARAIAAGTRETPPPALAERAAVMAAHLEGLLACHGLERGLKTSRKHMGWYARTMPQG
ADFRAAYMAAADAGAARRVLNHFTALWQSAPPSASQESRQRAVLKNPTPEDTSPDRPREE
AA