Protein Info for Rru_A1634 in Rhodospirillum rubrum S1H

Annotation: NADH dehydrogenase (quinone) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 35 to 58 (24 residues), see Phobius details amino acids 81 to 104 (24 residues), see Phobius details amino acids 116 to 142 (27 residues), see Phobius details amino acids 167 to 189 (23 residues), see Phobius details amino acids 208 to 227 (20 residues), see Phobius details amino acids 233 to 253 (21 residues), see Phobius details amino acids 257 to 276 (20 residues), see Phobius details amino acids 282 to 299 (18 residues), see Phobius details amino acids 308 to 328 (21 residues), see Phobius details amino acids 332 to 355 (24 residues), see Phobius details amino acids 374 to 395 (22 residues), see Phobius details amino acids 412 to 434 (23 residues), see Phobius details amino acids 455 to 476 (22 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 132 to 423 (292 residues), 190.9 bits, see alignment E=1.5e-60

Best Hits

KEGG orthology group: K05903, NADH dehydrogenase (quinone) [EC: 1.6.99.5] (inferred from 100% identity to rru:Rru_A1634)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3, 1.6.99.5

Use Curated BLAST to search for 1.6.5.3 or 1.6.99.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTW1 at UniProt or InterPro

Protein Sequence (490 amino acids)

>Rru_A1634 NADH dehydrogenase (quinone) (NCBI) (Rhodospirillum rubrum S1H)
MSAAPALSLAWILATPLAATLVIALNAKRPRLGEAIGVIAALLTFAQVAALTPTVLAGGR
PTLVMLSVMDTIPLVFTLDPLGLLFALVAAALWIPAGLYSIAYLRANHEAHQPRFHAYFA
LAIACTLGIALAGNLFTLFLFYEALTLSTYPLITHQGTAQAVRAGRIYMGMLLVPSIGLL
LVAIILTHSLAGRMDFQPGGILAGRIDGPLVGLLLALFVFGTAKAALMPFHRWLPAAMVA
PTPVSALLHAVAVVKAGVFTIAKVVISIFGIDLLAASSWTGWLTWVAGISVILASLIALR
QDNLKRRLAYSTISQLAYVVMALSLFSPLGVLAAGLHIVVHAFGKITLFFAAGAIHTATH
KDSVSQFAGIGRAMPWTMGAFAVASLSMIGLPPTAGFLSKWGIFSAAFQGQTWGVVAVLI
ASTVLNAAYFLPILHTAFLKPPPGEAGAKIAEAPPLMVAALCLTAFGTLALFFLPGLPFT
LARQLAGVGP