Protein Info for Rru_A1566 in Rhodospirillum rubrum S1H

Annotation: NADH-plastoquinone oxidoreductase, chain 5 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 643 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 53 (22 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 114 to 131 (18 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 177 to 203 (27 residues), see Phobius details amino acids 211 to 233 (23 residues), see Phobius details amino acids 254 to 272 (19 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 312 to 338 (27 residues), see Phobius details amino acids 344 to 361 (18 residues), see Phobius details amino acids 379 to 400 (22 residues), see Phobius details amino acids 420 to 441 (22 residues), see Phobius details amino acids 465 to 488 (24 residues), see Phobius details amino acids 519 to 539 (21 residues), see Phobius details amino acids 619 to 639 (21 residues), see Phobius details TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L" amino acids 2 to 638 (637 residues), 862 bits, see alignment E=1.9e-263 PF00662: Proton_antipo_N" amino acids 65 to 115 (51 residues), 74.2 bits, see alignment 9.5e-25 PF00361: Proton_antipo_M" amino acids 131 to 421 (291 residues), 291.6 bits, see alignment E=9.4e-91 PF06455: NADH5_C" amino acids 514 to 628 (115 residues), 30.5 bits, see alignment E=4.2e-11

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 100% identity to rru:Rru_A1566)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RU29 at UniProt or InterPro

Protein Sequence (643 amino acids)

>Rru_A1566 NADH-plastoquinone oxidoreductase, chain 5 (NCBI) (Rhodospirillum rubrum S1H)
MLYFLAVFLPLLTAIATGFFGRALGDKGAQRLTCLGMAISALFSWFIFFDTALGGNNTTV
TLFTWVISGDLHFDWALKIDTLSAVMLMVVTTISFMVHIYSVGYMHHDASVPRFMAYLSL
FTFFMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPSANAAAIKAFVVNRVGDFGFT
LGIFGVFFVFGTVGLDAIFAGAAQHANDVVTFFGIEWHAMTILCLLLFIGAMGKSAQLGL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFVLSDTAMTVVTIVGASTAIFAA
TVGCVQNDIKRVIAYSTCSQLGYMFFALGVGAFGAGIFHLMTHAFFKALLFLGAGSVIHA
MSDEQDMRRMGGIWRMVPLTYALMWIGSLALMGVPPFAGFFSKDMILEVAYAAHGGAGAY
AFWLGILAATLTAFYSTRLIIMTFHGAPRADEHVMAHVHESPRVMTLPLIVLAIGAVVAG
GLGADAFIGDGRFAFWGTAIAQSAEDVTHHAHDVPGWVKLLPLVVTALGVGLGVFLYGVR
PKLPAKLAASAPGLYRFLLNKWYFDELYDRIFIKPAFLLGRGFWKDGDGAIIDGVGPDGV
ASATRSLARWFGRMQTGYLYHYAFAMITGIAGVVTWVMVTSAH