Protein Info for Rru_A1526 in Rhodospirillum rubrum S1H

Annotation: Cobyrinic acid a,c-diamide synthase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 PF10609: ParA" amino acids 4 to 44 (41 residues), 28.2 bits, see alignment 4.5e-10 PF13614: AAA_31" amino acids 4 to 48 (45 residues), 43.5 bits, see alignment 1.3e-14 amino acids 74 to 119 (46 residues), 32.1 bits, see alignment 3.9e-11 PF07015: VirC1" amino acids 4 to 179 (176 residues), 39.2 bits, see alignment E=1.8e-13 PF09140: MipZ" amino acids 5 to 48 (44 residues), 25.3 bits, see alignment 3.2e-09 PF01656: CbiA" amino acids 6 to 185 (180 residues), 56.2 bits, see alignment E=1.2e-18

Best Hits

KEGG orthology group: K03496, chromosome partitioning protein (inferred from 100% identity to rru:Rru_A1526)

Predicted SEED Role

"Chromosome (plasmid) partitioning protein ParA" in subsystem Bacterial Cytoskeleton or Plasmid replication or Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RU69 at UniProt or InterPro

Protein Sequence (212 amino acids)

>Rru_A1526 Cobyrinic acid a,c-diamide synthase (NCBI) (Rhodospirillum rubrum S1H)
MAARIITIAQQKGGAGKTTLVAQLAVAYAALGRTVALVDIDPQGSLAAWHRLRGETLDAG
AGGLHLSDVAGWRLGTELDRLRNSYDIVIVDTPPHAETEARTAVRAGDIVLVPIQPSPMD
LWATAATLDLARKERTEVLLVLNRVPPRGRLPEVIEARLQADDLPIAKTRIGNRTALAAS
LLEGKGVVETDRGSRAAEEIRALAGEVLAHLS