Protein Info for Rru_A1361 in Rhodospirillum rubrum S1H
Annotation: Glycerone kinase (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 49% identical to DHAK2_LISIN: PTS-dependent dihydroxyacetone kinase 2, dihydroxyacetone-binding subunit DhaK (dhaK-2) from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
KEGG orthology group: K05878, dihydroxyacetone kinase, N-terminal domain [EC: 2.7.1.-] (inferred from 100% identity to rru:Rru_A1361)Predicted SEED Role
"Putative dihydroxyacetone kinase (EC 2.7.1.29), dihydroxyacetone binding subunit" in subsystem Dihydroxyacetone kinases (EC 2.7.1.29)
MetaCyc Pathways
- formaldehyde assimilation III (dihydroxyacetone cycle) (11/12 steps found)
- glycerol degradation to butanol (12/16 steps found)
- glycerol degradation II (1/2 steps found)
- superpathway of glycerol degradation to 1,3-propanediol (1/4 steps found)
KEGG Metabolic Maps
- Glycerolipid metabolism
- Lipopolysaccharide biosynthesis
- Nicotinate and nicotinamide metabolism
- Pentose phosphate pathway
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.-, 2.7.1.29
Use Curated BLAST to search for 2.7.1.- or 2.7.1.29
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RUN3 at UniProt or InterPro
Protein Sequence (333 amino acids)
>Rru_A1361 Glycerone kinase (NCBI) (Rhodospirillum rubrum S1H) MTRPKKLLNDPLRVVEESLEGLVFASDGEMRLLPGYTIALRSSLRDDKVALLIGGGSGHE PMFAGYVGKGLADGAVCGQMFAAPTPDAILEATRAVNKGKGVLYIYGNYSGDNMNFDIAA ELAEEEGITTKTVRVRDDVAAAPIERIDDRRGIAGDVFVIKVAGAAAEVCDSLDELYRIA AKAEANTHSIGVAVAAGSIPETGEATFEIGDDEIEIGMGAHGEPGTRRQKIAPADAVVDE MMDMLLADMGLAAGDEVALLIDNLGSSTAMELYIANRRVRQRLAQAGVQVHLTEVGPFMT SQEMAGFSITMMRLDEELKRFIDAPARSAAYTR