Protein Info for Rru_A1300 in Rhodospirillum rubrum S1H

Annotation: N-formylglutamate deformylase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02017: N-formylglutamate deformylase
  • amino acids 5 to 262 (258 residues), 339.3 bits, E=7.8e-106
• PF05013: FGase
  • amino acids 12 to 233 (222 residues), 247.1 bits, E=1.1e-77

Best Hits

KEGG orthology group: K01458, N-formylglutamate deformylase [EC: 3.5.1.68] (inferred from 100% identity to rru:Rru_A1300)

MetaCyc: 52% identical to N-formylglutamate amidohydrolase (Pseudomonas putida)
N-formylglutamate deformylase. [EC: 3.5.1.68]

Predicted SEED Role

"N-formylglutamate deformylase (EC 3.5.1.68)" in subsystem Histidine Degradation (EC 3.5.1.68)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Histidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.68

Use Curated BLAST to search for 3.5.1.68

Sequence Analysis Tools

See Q2RUU4 at UniProt or InterPro

Protein Sequence (264 amino acids)

>Rru_A1300 N-formylglutamate deformylase (NCBI) (Rhodospirillum rubrum S1H)
MTAVYDLIEGESPLIVSIPHCGTTLPPGLIDRLSPPARLLPDTDWHVERLYDFARGLGAT
VIAARLSRFVIDLNRPADGASLYPGQATTGLCPTTLFSGVPLYLPGAEPTPTEIAARVEN
YWRPYHRALAGELARLKARHGHAILYDAHSIRAEVPRLFEGRLPDLNLGTAGGASLSPAF
APLLDDWRGEAEAAGFTTVLNGRFIGGHITRAYGQPADNIHALQMELVQQRYMDEESYAY
LPERADRLRPLLHRLLDQLIAWRP