Protein Info for Rru_A1292 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF214 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 420 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 268 to 285 (18 residues), see Phobius details amino acids 293 to 315 (23 residues), see Phobius details amino acids 337 to 361 (25 residues), see Phobius details amino acids 388 to 410 (23 residues), see Phobius details PF02687: FtsX" amino acids 298 to 412 (115 residues), 51.7 bits, see alignment E=4.7e-18

Best Hits

KEGG orthology group: K02004, (no description) (inferred from 100% identity to rru:Rru_A1292)

Predicted SEED Role

"ABC-type antimicrobial peptide transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RUV2 at UniProt or InterPro

Protein Sequence (420 amino acids)

>Rru_A1292 Protein of unknown function DUF214 (NCBI) (Rhodospirillum rubrum S1H)
MLRFVFADLATRRWGAAALVVIIALATGLGVMVTLQERALRLGSARAAAAFDLVIGAPGS
ETQLVLSSVFLQAAPLTLMPGNVLAKLAADPRVAYAAPVGFGDFVGDHPIVGTTLDLVSG
LGGVTEGRGFEKLSEAVIGAKVEISLGQQIQPMHGHAEEGGEAHAGVSYRVVGRLAASGT
PWDRAVLVPIEAVWRVHGHWAPDHDHEHEEEHGHGADEHDHDHAGESDLDDPLRPEAIFD
ALAPGVPAILVKPRGIAEAYKLRQEYRAAPTMAVFPAEVLTRLYGTMGDARRILAMVAAG
AQALVGAAILLVITVEVLQRRRQIGALRAFGAPRRAIFALVWVEAFALLLAGLLGGFALG
YGGSLALARGLERTGGIDLPVVFEAGDAVYGLILLGVGALFALLPAALAYRQSPLAALRG