Protein Info for Rru_A1282 in Rhodospirillum rubrum S1H

Annotation: Two component Transcriptional regulator, Winged helix family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 PF00072: Response_reg" amino acids 6 to 114 (109 residues), 111.6 bits, see alignment E=2.3e-36 PF00486: Trans_reg_C" amino acids 154 to 229 (76 residues), 89.8 bits, see alignment E=9.7e-30

Best Hits

Swiss-Prot: 45% identical to ARCA_ECOLI: Aerobic respiration control protein ArcA (arcA) from Escherichia coli (strain K12)

KEGG orthology group: K07772, two-component system, OmpR family, torCAD operon response regulator TorR (inferred from 100% identity to rru:Rru_A1282)

Predicted SEED Role

"TorCAD operon transcriptional regulatory protein TorR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RUW2 at UniProt or InterPro

Protein Sequence (249 amino acids)

>Rru_A1282 Two component Transcriptional regulator, Winged helix family (NCBI) (Rhodospirillum rubrum S1H)
MANHHILVVEDDPVGRETLAAYLRKEGYKVSDVEDGDSMRKVFSQQTVDLILLDIRLPGV
DGLQLLREIRHQSEVGVIMVTGKDDEVDRIVALEMGADDYVTKPFNVRELLARAKNLLRR
TLSAREASEDENQKSFAGWTLDIPRRCLFAPDGSDVRLTRGEFELLCCFASRPGRVMTRD
NLLDYVSHRDWAPSDRTVDVLVGRLRRKIEADPKAPRHIITVHGIGYVFADSRHIEPGSP
EKSAARQGG