Protein Info for Rru_A1276 in Rhodospirillum rubrum S1H

Annotation: ATP-cone (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 673 PF03477: ATP-cone" amino acids 12 to 99 (88 residues), 84.1 bits, see alignment E=8.5e-28 TIGR02487: anaerobic ribonucleoside-triphosphate reductase" amino acids 128 to 663 (536 residues), 462.7 bits, see alignment E=9.1e-143 PF13597: NRDD" amino acids 129 to 660 (532 residues), 565.7 bits, see alignment E=1.2e-173

Best Hits

KEGG orthology group: K00527, ribonucleoside-triphosphate reductase [EC: 1.17.4.2] (inferred from 100% identity to rru:Rru_A1276)

Predicted SEED Role

"Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)" in subsystem Ribonucleotide reduction (EC 1.17.4.2)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.17.4.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RUW8 at UniProt or InterPro

Protein Sequence (673 amino acids)

>Rru_A1276 ATP-cone (NCBI) (Rhodospirillum rubrum S1H)
MIPEIVSPPPGVVKRSGRTVPFDAVKIRSAIERAGKATGDFDPIEAQLLAIQAVKVLSHR
FTEDAPHIEQIQDVVEQVLISANHFATARAYIVYREQHARLRIDRKTVVDVESSINEYLD
RADWRVNANANQGYSLGGLILNVSGKVVANYWLSHVYPPEIGNAHRQGDLHIHDLDMLAG
YCAGWSLRTLLTEGLNGVPGKVEAGPPKHLSSAVGQIVNFLGTLQNEWAGAQAFSSFDTY
LAPFVRADRLSYAEVRQFIQELVYNLNVPSRWGTQTPFTNLTFDWTCPEDLRDQVPVIGG
VEVDFTYGDLQVEMDLINRAYMEVMTEGDAKGRVFTFPIPTYNITKDFPWDSENADRLFE
MTAKYGLPYFQNFVNSELNPSMIRSMCCRLQLDLTELLKRGNGLFGSAEQTGSLGVVTLN
CARLGYIHQGDEAGLFARLDTLLDLGRNSLEIKRKVIQRHMDHGLFPYTKRYLGTLRNHF
STLGVNGINEMIRNFTAGAEDITTPYGHALAVRFLDHVRARIVGFQEETGHLYNLEATPA
EGTTYRFAREDQKRFPDILQAGTPDQPYYTNSSQLPVGFTDDPFEALERQEELQAKYTGG
TVVHLYMGSRVSSAEACKRLVRRALERFRLPYITVTPTFSICPTHGYIEGEHAFCPKCDE
DIIARKRAKSACC