Protein Info for Rru_A1121 in Rhodospirillum rubrum S1H

Annotation: Pyruvate carboxylase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1153 PF00289: Biotin_carb_N" amino acids 9 to 118 (110 residues), 147.8 bits, see alignment E=5.7e-47 TIGR01235: pyruvate carboxylase" amino acids 11 to 1151 (1141 residues), 1789.7 bits, see alignment E=0 PF02786: CPSase_L_D2" amino acids 124 to 328 (205 residues), 227.2 bits, see alignment E=5.9e-71 PF02785: Biotin_carb_C" amino acids 352 to 460 (109 residues), 111.3 bits, see alignment E=9.2e-36 PF00682: HMGL-like" amino acids 542 to 812 (271 residues), 84.5 bits, see alignment E=3.3e-27 PF02436: PYC_OADA" amino acids 835 to 1034 (200 residues), 253.3 bits, see alignment E=6.2e-79 PF13533: Biotin_lipoyl_2" amino acids 1085 to 1118 (34 residues), 23.6 bits, see alignment (E = 1.3e-08) PF00364: Biotin_lipoyl" amino acids 1085 to 1149 (65 residues), 54.6 bits, see alignment 2.7e-18

Best Hits

KEGG orthology group: K01958, pyruvate carboxylase [EC: 6.4.1.1] (inferred from 67% identity to amv:ACMV_29950)

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.4.1.1

Use Curated BLAST to search for 6.4.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVC3 at UniProt or InterPro

Protein Sequence (1153 amino acids)

>Rru_A1121 Pyruvate carboxylase (NCBI) (Rhodospirillum rubrum S1H)
MTSQSPRKITKILVANRGEIAIRVFRAANESGIRTVAIYAEEDKLSLHRFKADESYLIGT
GMGPVRAYLSIDEILRVARQSGADAIHPGYGFLSENPEFAEACAEAGLIFIGPPPEVMRS
LGNKVSARAMAEAADVPVMPATGPLPEEIDLIRPMAEKVGYPLMLKASWGGGGRGMRVIN
TPDELERQVSAGRREAEAAFGNGEVYLEKLVLRARHVEVQLLGDHYGTVVHLFERDCSVQ
RRNQKVVERAPAPYLTPEKREEVCEAALRLARAAGYVCAGTAEFLMDADTGDFHFIEVNP
RIQVEHTVTEEVTGIDLVKAQIRICEGGHIGVVEETGVPAQADLRLQGHAIQCRITTEDP
EANFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRYYDSLLEKVTAWAPTPKEAIDRL
DRALREFRIRGVATNLAFVENLINHPKFREASYTTRFIDETPELFHFDRRLDRATKLLRF
IADVTVNGNPEVKGRVLPTPGPAPRLPIVQAQEPPRGTRQILAELGPTGFAEWMLDQKRT
LVTDTTFRDAHQSLLATRMRSFDMIQVADAYARNLPELFSLECWGGATFDVAMRFLRECP
WERLAELRQRVPNILFQMLLRGANGVGYTVYPDNVVKGFTHKAAEAGVDLFRVFDSLNWV
ENMRVSMDAVLETGKLLEGVVCYTGDINDPERSKYDLKYYVSMARELRKAGSHIIGIKDM
AGLVKPRAAYALVKALKEETGLPVHFHTHDTSGISAASVLEAVRAGVDAIDAAMDSFSGL
TSQPCLGSIVEALRFSERDTGLDPLIVRQVSDYWEGVRRQYAGFESDLRSGASEVYLHEM
PGGQFTNLKEQARAMGLAGHWHEVARTYAEVNQMFGDIVKVTPSSKVVGDMALYMVGAGL
TRADVEDPDKDVSFPESVVSLMRGELGHPPEGFPEALQRKVLRGQAPLAGRPGAAVPPAD
LAAERKTAEEKAGRAISDEEFQSYLMYPKVFIDYAKQRAEFGPVRVLPTPIFFYGMKPGQ
ETAVTLEAGKTLVIRCQALGETDEEGMIKVFFELNGQPRVVRVVNRAVKSTVIQHEKADP
ANPTHVACPMPGLVSSVGVSVGQTVRAGDPLLTIEAMKMETSITAERAGVIERLPIAAGT
AVEAKDLLVVYKG