Protein Info for Rru_A1105 in Rhodospirillum rubrum S1H
Annotation: tRNA synthetase, class II (G, H, P and S) (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to HISZ_RHORT: ATP phosphoribosyltransferase regulatory subunit (hisZ) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
KEGG orthology group: K02502, ATP phosphoribosyltransferase regulatory subunit (inferred from 100% identity to rru:Rru_A1105)Predicted SEED Role
"ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)" in subsystem Histidine Biosynthesis (EC 2.4.2.17)
MetaCyc Pathways
- superpathway of histidine, purine, and pyrimidine biosynthesis (42/46 steps found)
- L-histidine biosynthesis (10/10 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of plant hormones
- Histidine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.4.2.17
Use Curated BLAST to search for 2.4.2.17
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RVD9 at UniProt or InterPro
Protein Sequence (384 amino acids)
>Rru_A1105 tRNA synthetase, class II (G, H, P and S) (NCBI) (Rhodospirillum rubrum S1H) MTVTAKTAARALLPNGLRDVLPPDAAFEVATVERLVSVFAANGYERVKTPLIEFEEGLLT GASRATAGQTFRVMDPITQRMMGLRADITIQVARLAASRLAKAPRPLRLTYSGQVLRVKG TQLRPERQFTQAGIELIGAGGVDAIAESVLLTVEALAQAGLPRVTVDLNCPPLVPALCRA LGLSEDLAGELRKLLEQKDFTAAAALAGDAAGALSALSGTVGPAERALPVLAALDLPGEA AGHRDALLALARKVMTAAPEVDVTVDPLEHKGFEYYTGCSFALFAQGARGELGRGGEYPG DLNGTVEPCCGATLYMDAVLDGMVRPAPAPRVLVASTLARTTRRALQADGWVTVPALTAE AGAAEARRLGCGHVLDDEGRPVAV