Protein Info for Rru_A1079 in Rhodospirillum rubrum S1H

Annotation: sodium/hydrogen exchanger (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 34 to 55 (22 residues), see Phobius details amino acids 61 to 78 (18 residues), see Phobius details amino acids 87 to 110 (24 residues), see Phobius details amino acids 123 to 144 (22 residues), see Phobius details amino acids 169 to 183 (15 residues), see Phobius details amino acids 196 to 219 (24 residues), see Phobius details amino acids 227 to 258 (32 residues), see Phobius details amino acids 278 to 297 (20 residues), see Phobius details amino acids 307 to 328 (22 residues), see Phobius details amino acids 339 to 362 (24 residues), see Phobius details amino acids 368 to 387 (20 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 21 to 393 (373 residues), 152.5 bits, see alignment E=1.5e-48 PF03471: CorC_HlyC" amino acids 497 to 569 (73 residues), 42.9 bits, see alignment E=4e-15

Best Hits

KEGG orthology group: K11105, cell volume regulation protein A (inferred from 100% identity to rru:Rru_A1079)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVG5 at UniProt or InterPro

Protein Sequence (610 amino acids)

>Rru_A1079 sodium/hydrogen exchanger (NCBI) (Rhodospirillum rubrum S1H)
MEMDTMFLAILIGAGLIGISVVTSLISFRVGAPLLLVFLGVGLLAGQDGIGGIVFNDSGT
AYFIGSLALAVILFDSGFSTRLQTFRLAAAPSIVLATLGVALTTALVAIPSHSLLGLSWE
ESALMGAVVGSTDAAAVFFLLRVGGILIRDRVRATLEVESSTNDPMAIFLTITLVELASA
GGFSGEALSWGLGLAFVRQMGLGLLCGWIGGHLLVVGINRLRLEPALYPILGLALALFLF
AAVSMVDGSGFLAIYVAGMVMGNRKMRGGPALRRFQEALTWLAQMTMFLTLGLFASPSTF
IDVALPSVLIGLFLVFVARPVAVWLCLLPFGYDRNETAFVAWVGLRGAVSILLAILPIAA
GLEHAQEMFNAAFIVVVTSLLLQGWTIRPMARWLGLVVPPRLGPVDKVELQLPYGGDHEL
LVYRIAKGSPVAEGERIPRWARPSLVVRDGRSMKVLDSGRPQPGDHVYIFSAPRHGALLD
RLFARPTALSPADEAYFGDFSLDASRTMGELATLYGIKVPEGAQDTAVGEWLTQRLGGAP
ARGDRVVLPPIEIIVREMDNSTDVIRTIGLSLDPGEGRPRRVPMFHNARDIIGSVRDWRA
ARRRFAAKNS