Protein Info for Rru_A1078 in Rhodospirillum rubrum S1H

Annotation: tRNA synthetase, class II (D, K and N) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 PF00152: tRNA-synt_2" amino acids 19 to 352 (334 residues), 160.5 bits, see alignment E=2.7e-51 TIGR00462: EF-P lysine aminoacylase GenX" amino acids 22 to 352 (331 residues), 386.8 bits, see alignment E=4e-120

Best Hits

KEGG orthology group: K04568, lysyl-tRNA synthetase, class II [EC: 6.1.1.6] (inferred from 100% identity to rru:Rru_A1078)

Predicted SEED Role

"Translation elongation factor P Lys34:lysine transferase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.6

Use Curated BLAST to search for 6.1.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVG6 at UniProt or InterPro

Protein Sequence (358 amino acids)

>Rru_A1078 tRNA synthetase, class II (D, K and N) (NCBI) (Rhodospirillum rubrum S1H)
MPPISPPWFHPDSHARRRPFLLARARAAAAIRAFLGESGCIEVDTPALQISPGLEPHLRA
FATTLEKPFDQGRATLRLHTSPEFAMKKILAAGETAIFQLAHVFRNGERGPTHHPEFTML
EWYRSAMSYEALMAETEDLVRAVARATGAERLVWGDAAADPFGPWERLSVAQALERYAGI
DLLGALDAGVAISGNALEPDAGALAEAARAIGIACSPNDRFEDVFFRIVLDRVEHRLGHE
RPCILYDYPACMAALSRRKDDDPRLAERFEVYVGGLELANAFGELTDAAEQRARFTHDMD
VKEALYGERYPIDGDFLEALDQGLAPCSGIALGFDRLVMLCTGADAIDDVLWAPVADP