Protein Info for Rru_A1065 in Rhodospirillum rubrum S1H

Annotation: Plasmid maintenance system antidote protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 101 TIGR02607: addiction module antidote protein, HigA family" amino acids 4 to 82 (79 residues), 102.5 bits, see alignment E=4.3e-34 PF01381: HTH_3" amino acids 19 to 69 (51 residues), 40.6 bits, see alignment E=2.1e-14

Best Hits

Swiss-Prot: 42% identical to Y1251_HAEIN: Uncharacterized HTH-type transcriptional regulator HI_1251 (HI_1251) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A1065)

Predicted SEED Role

"HigA protein (antitoxin to HigB)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVH9 at UniProt or InterPro

Protein Sequence (101 amino acids)

>Rru_A1065 Plasmid maintenance system antidote protein (NCBI) (Rhodospirillum rubrum S1H)
MMTKRKPVTVGEILVEEFMGPLGLTQAALAEAMGVQRKHVNELCNNRRTVTAATALILAR
VFGNSPDFWLNAQRRNDLWEVLHSPKDVERIERAKPLALRA