Protein Info for Rru_A1035 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 917 signal peptide" amino acids 1 to 11 (11 residues), see Phobius details transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 296 to 319 (24 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 344 to 467 (124 residues), 28.6 bits, see alignment E=1.3e-10 PF08447: PAS_3" amino acids 374 to 458 (85 residues), 35.9 bits, see alignment E=1.1e-12 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 473 to 638 (166 residues), 156.1 bits, see alignment E=6.8e-50 PF00990: GGDEF" amino acids 476 to 634 (159 residues), 175.2 bits, see alignment E=1.4e-55 PF00563: EAL" amino acids 658 to 889 (232 residues), 214.8 bits, see alignment E=1.8e-67

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A1035)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVK9 at UniProt or InterPro

Protein Sequence (917 amino acids)

>Rru_A1035 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI) (Rhodospirillum rubrum S1H)
MLRIPSRSDSRFVLFLCSTALLVTAFAFFATYGGLKELRARDVWRAEAHSKDLTKAIRQS
TTNYLEKVEISLNTIAYVIEKDNHIGKREKEQIENLLSNQFLIFRDNENISITNEKGEII
FHEGLNTPLNFSVSDRDYFISLKNGTKTGLVASPVLISRLSKKPVIIFSRSYTKADGTFG
GIVAMPVPTDRFQHLVSGYTLGGRDRLSLFSEDRSLIVSTEPTTIGAKAPANPAPPHPFD
DRPDHPIQDGTQRHIDPSDNTTNIITIAQIPSADMHVLCEISEDDYLSEWYETRNISLLF
VAFFLSLFYLSLFILYFFWRRQKEDATRLRESNEQTQTVLRTLRESDNALAAACEVGGLS
TFILDLSANLWMRSPEQEAIFGLDGRHPRTRDAWHALIYPEDRGGVLDYFAERDALDTGE
FDIQYRIIRPSDGAVRWIHGAGKLERAEDLSVRRLVGAIKDVTEIKEDLDRTEFLAYHDS
LTNLPNRLLLADRMGQALALAVRRQDLLAVCYLDLDSFKPINDTWGHSVGDALLIEVARR
LQQNARAEDTVARLGGDEFVVLLCGFKAEAEVERVVRRMMDSIATPYSVGGRQVTLTVSM
GITTFPRDAEQEADALIRHADQAMYEAKRQGRNRIHYFDAEKDRLHKERQTYYNRMVAAL
EANEFQLHYQPTIDLVSGVFSGVEALIRWRHPERGLLLPGAFLPDIEDTDLTVPLGEWIL
REALRQKERWQDMGLSLTVGVNLFGYHLQQDSFVARFAAILAEFPAVHPEEVTLEIVETT
AMRDLAAISEKMWDCKRFGVDFALDDFGTGYSSLTYFRRLPVTHLKIDRSFVTDILENAQ
DQAMVQSIVAMSHALGRKVVAEGAETLAHCAALGRYGCDFAQGFGIARPMPGEDIFPWAR
QWNRPDSLRVSLGEAFA