Protein Info for Rru_A0956 in Rhodospirillum rubrum S1H

Annotation: Peptidoglycan glycosyltransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 599 transmembrane" amino acids 49 to 69 (21 residues), see Phobius details PF03717: PBP_dimer" amino acids 95 to 221 (127 residues), 51.6 bits, see alignment E=1.6e-17 PF00905: Transpeptidase" amino acids 256 to 539 (284 residues), 177.8 bits, see alignment E=3.1e-56

Best Hits

KEGG orthology group: K03587, cell division protein FtsI (penicillin-binding protein 3) [EC: 2.4.1.129] (inferred from 100% identity to rru:Rru_A0956)

Predicted SEED Role

"Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Flagellum in Campylobacter or Peptidoglycan Biosynthesis (EC 2.4.1.129)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVT8 at UniProt or InterPro

Protein Sequence (599 amino acids)

>Rru_A0956 Peptidoglycan glycosyltransferase (NCBI) (Rhodospirillum rubrum S1H)
MIALLKNRREKRFVYPGAEIRFDRTAERGRGADLEGVVHQGIETGRMRLMVAACLFGLAF
SVIGGRLVQLMVVRGPGEPVAVVSAEDTPIETRMARADIVDRNGLVLATNLPTVNLYADT
RAIPERDRLRAIAVLPTLFPELTVADLTNKMVPGRAFIYLRRNLTPSEQQSVNDLGIPGL
HFERSERRVYPAGRLVAHVVGATDVDNNGIAGLEKAFESKLTSSDLPLRLSLDIRVQHAI
HRALQDSIDHFQAIGGAALVMDVETAEVVAMVSLPDYEPEKIGAASEDARFNRATLGVFE
MGSTFKLFNTALALDAGLKLSESFDARNPIRISRFTITDFHPEGRWLSIPEILMYSSNLG
SARMAVAVGTDRQREFLGRMGLLDAIPFEIPEVGRPLVPNPWREVSTMTISFGHGLSVTP
LHLVTGVSALVNGGLLRPPTLLLRSPETTPAGKQVLTTQNSTAMRALMRLVVEAGSGKNA
DVKGYYIGGKTGSAEKEGASGGYSKSAVRTSFVGVFPMTKPRYVVMAMLDDPKAVKGTYG
YRTAGWNATPTVGRMIAEIAPLLGVQPVRGDPAVQFGPQLVQQVGLRFAEPEGGRGVSR