Protein Info for Rru_A0953 in Rhodospirillum rubrum S1H

Annotation: Phospho-N-acetylmuramoyl-pentapeptidetransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 73 to 91 (19 residues), see Phobius details amino acids 97 to 114 (18 residues), see Phobius details amino acids 134 to 152 (19 residues), see Phobius details amino acids 173 to 192 (20 residues), see Phobius details amino acids 200 to 224 (25 residues), see Phobius details amino acids 239 to 256 (18 residues), see Phobius details amino acids 263 to 282 (20 residues), see Phobius details amino acids 288 to 311 (24 residues), see Phobius details amino acids 338 to 357 (20 residues), see Phobius details TIGR00445: phospho-N-acetylmuramoyl-pentapeptide-transferase" amino acids 38 to 360 (323 residues), 432.9 bits, see alignment E=4.4e-134 PF10555: MraY_sig1" amino acids 68 to 80 (13 residues), 21.6 bits, see alignment (E = 1.1e-08) PF00953: Glycos_transf_4" amino acids 99 to 283 (185 residues), 117.7 bits, see alignment E=5.1e-38

Best Hits

Swiss-Prot: 100% identical to MRAY_RHORT: Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K01000, phospho-N-acetylmuramoyl-pentapeptide-transferase [EC: 2.7.8.13] (inferred from 100% identity to rru:Rru_A0953)

MetaCyc: 54% identical to phospho-N-acetylmuramoyl-pentapeptide-transferase (Escherichia coli K-12 substr. MG1655)
Phospho-N-acetylmuramoyl-pentapeptide-transferase. [EC: 2.7.8.13]

Predicted SEED Role

"Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13)" in subsystem Peptidoglycan Biosynthesis (EC 2.7.8.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVU1 at UniProt or InterPro

Protein Sequence (360 amino acids)

>Rru_A0953 Phospho-N-acetylmuramoyl-pentapeptidetransferase (NCBI) (Rhodospirillum rubrum S1H)
MLYFLSELTAQVSALNVFRYLTFRTGGAVMTAMLVAFVFGPGIIEWLKRKQGEGQPIRSD
GPESHLTKKGTPTMGGIMILLGVGVATLLWADLSKGYVWAVLLLTLGYGAIGFADDYLKL
TKRNTKGLSGRLKLVAQVGMAVIAGLWIMLLGQGDQASSLALPFFKDLTFNLGWFYLPFA
AFVMVGASNAVNLTDGLDGLAIVPVMIAAGVFMLIAYLVGNIIFSNYLQIQHVPGTGELA
VFCGAIVGAAVGFLWFNAPPAMVFMGDTGSLALGGALGAVSVVTKHEIVLAIVGGLFVLE
TVSVIVQVASFKLTGKRVFRMAPLHHHFEKKGWAEPTVVIRFWIIAMILAIVGLSTLKLR