Protein Info for Rru_A0834 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF196 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 95 PF09827: CRISPR_Cas2" amino acids 1 to 77 (77 residues), 87.9 bits, see alignment E=2e-29 TIGR01573: CRISPR-associated endonuclease Cas2" amino acids 2 to 89 (88 residues), 60.4 bits, see alignment E=8e-21

Best Hits

Swiss-Prot: 100% identical to CAS2C_RHORT: CRISPR-associated endoribonuclease Cas2 3 (cas2-3) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0834)

Predicted SEED Role

"CRISPR-associated protein Cas2" in subsystem CRISPRs

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RW60 at UniProt or InterPro

Protein Sequence (95 amino acids)

>Rru_A0834 Protein of unknown function DUF196 (NCBI) (Rhodospirillum rubrum S1H)
MILVTYDVNTVEPGGRRRLRQVAKACQDYGQRVQNSVFEVEVDPARWVALKARLEAIIDP
ALDSLRYYDLGANWQRRVDHVGAKPAVDLHGPLIL