Protein Info for Rru_A0684 in Rhodospirillum rubrum S1H
Annotation: hypothetical protein (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: K00763, nicotinate phosphoribosyltransferase [EC: 2.4.2.11] (inferred from 100% identity to rru:Rru_A0684)Predicted SEED Role
"Nicotinate phosphoribosyltransferase (EC 2.4.2.11)" in subsystem NAD and NADP cofactor biosynthesis global or NAD regulation or Redox-dependent regulation of nucleus processes (EC 2.4.2.11)
MetaCyc Pathways
- NAD salvage pathway I (PNC VI cycle) (6/7 steps found)
- NAD salvage pathway V (PNC V cycle) (4/5 steps found)
- NAD salvage (plants) (6/11 steps found)
- superpathway of NAD biosynthesis in eukaryotes (6/14 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Nicotinate and nicotinamide metabolism
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.4.2.11
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RWK7 at UniProt or InterPro
Protein Sequence (410 amino acids)
>Rru_A0684 hypothetical protein (NCBI) (Rhodospirillum rubrum S1H) MAPKEILAKSLTQGAPSPRDGAAMDRPADRWPSAIDVPRWTDKYFSRTAEVVRRFGDSQV TYAVFMRRPVLFAARLATDWLRAVCAERGTEVVIEALYKEADWVGAGEPMLHLTGSLIDL SELETLFLQKLGACCVAAYNAYHMCMDLPRVAFLAMDARHCAGTEMAELMAYAAAVGGER AQIKADAKGFIGNATDATAHYFGQAEGKGTMPHSLIGYAGSTVRAAEMFHETHPDVELVV LVDYFGQEITDALEVCRRFPDLAAEGRLGVRLDTHGGRFIEGLDTQTSYEVLERNASDAI RGYRSEPELRNLIGTGVSAAAIWHMREELDLAGYPKVRIVASSGFSPAKCRVMAYANTPI DVIGTGSFLPDNWNETYATADIIAYDGLPRVKVGREFLLKKREVPARDRG