Protein Info for Rru_A0658 in Rhodospirillum rubrum S1H

Annotation: Transcriptional Regulator, LysR family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR03298: transcriptional regulator, ArgP family" amino acids 2 to 297 (296 residues), 388.5 bits, see alignment E=8.5e-121 PF00126: HTH_1" amino acids 12 to 62 (51 residues), 55.4 bits, see alignment 4.9e-19 PF03466: LysR_substrate" amino acids 97 to 272 (176 residues), 52.8 bits, see alignment E=3.7e-18

Best Hits

Swiss-Prot: 39% identical to ARGP_PSEAB: HTH-type transcriptional regulator ArgP (argP) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 100% identity to rru:Rru_A0658)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RWN3 at UniProt or InterPro

Protein Sequence (310 amino acids)

>Rru_A0658 Transcriptional Regulator, LysR family (NCBI) (Rhodospirillum rubrum S1H)
MIDYPAALAVALVVQTGSFEKAAKALHVTPSAISQRVKMIEDRLGVSLIERGTPCIATEK
GEWLCRHMDHVGMLEKDLIKHMPGLAEAGADPLHRVTLTLATNADSLGTWFLGAVAPFAR
STDFLVSIAVDDEDYTADWLHRGRVLAAVTSLAKPVKGCRVTRLGALRYQATASPEFFER
YFARGVTPETLARAPALTFSQKDRLQRDWIRRTLGQSVSFPTHWLPSTQGFVDACLAGMG
WGMNPAQMVGAHLQAGRLVEILPGRTLDSPLFWQVNRLAADQLADLTRAVVGQASRALIQ
PSAESDPPEV