Protein Info for Rru_A0642 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF185 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 364 PF02636: Methyltransf_28" amino acids 64 to 300 (237 residues), 239.1 bits, see alignment E=2.6e-75

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0642)

Predicted SEED Role

"COG1565: Uncharacterized conserved protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RWP9 at UniProt or InterPro

Protein Sequence (364 amino acids)

>Rru_A0642 Protein of unknown function DUF185 (NCBI) (Rhodospirillum rubrum S1H)
MGAEPSRPPGAAVEALIARLRSGPLPVEDWMAACLGEYYARGDVLGAGGDFITAPECTQI
FGELLGLWSAVVWQAMGSPERINLVELGPGRGTLMADALRALAPVPAFRRALSVHLVETS
PGLRARQKQKLRASGVTVFWHERLDTVPSGPMIVLANEFLDALPIRQYLRDAEGWRERLV
GLAGEGPALTFTQGPLLGDPPPLAQPAHLQARVGEEIEVCPQAQAVVAQVAARLAADGGA
GLFLDYGPAHSAPGDSLQALRRHRFAAVLENPGAVDLTAHVDFQAMARVAAAAGAAVDGI
VQQGPFLQSLGLEARAGVLMANAATDQKREIRFAVRRLIDSSEMGTLFKVLGLRSPSMAR
LPGF