Protein Info for Rru_A0629 in Rhodospirillum rubrum S1H

Annotation: Geranylgeranyl reductase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 PF07992: Pyr_redox_2" amino acids 14 to 65 (52 residues), 31.8 bits, see alignment 4.8e-11 TIGR02032: geranylgeranyl reductase family" amino acids 14 to 318 (305 residues), 222.5 bits, see alignment E=1e-69 PF12831: FAD_oxidored" amino acids 15 to 46 (32 residues), 31 bits, see alignment (E = 8e-11) PF00890: FAD_binding_2" amino acids 15 to 45 (31 residues), 26.1 bits, see alignment (E = 2.3e-09) PF01266: DAO" amino acids 15 to 48 (34 residues), 29.2 bits, see alignment 3.2e-10 TIGR02023: geranylgeranyl reductase" amino acids 15 to 408 (394 residues), 447.2 bits, see alignment E=5e-138 PF01134: GIDA" amino acids 15 to 43 (29 residues), 23.1 bits, see alignment (E = 1.7e-08) PF13450: NAD_binding_8" amino acids 18 to 47 (30 residues), 25.1 bits, see alignment (E = 7.9e-09) PF01494: FAD_binding_3" amino acids 92 to 167 (76 residues), 23.1 bits, see alignment E=1.9e-08 PF05834: Lycopene_cycl" amino acids 246 to 350 (105 residues), 23.8 bits, see alignment E=1e-08

Best Hits

KEGG orthology group: K10960, geranylgeranyl reductase [EC: 1.3.1.83] (inferred from 100% identity to rru:Rru_A0629)

MetaCyc: 100% identical to geranylgeranyl-bacteriopheophytin reductase (Rhodospirillum rubrum)
RXN-17427 [EC: 1.3.1.111]

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.3.1.111 or 1.3.1.83

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RWR2 at UniProt or InterPro

Protein Sequence (413 amino acids)

>Rru_A0629 Geranylgeranyl reductase (NCBI) (Rhodospirillum rubrum S1H)
MDAVVATQTPAEVFDVVVVGGGPAGATAATDLARAGRRVALLDPEGRPKPCGGAIPPRLM
SEFAIPDDLPCAQVSGARALAPSGRVVDMPITGAVVSMVDRAVFDPWLRARAHQAGACRL
HGRFEGFDRQEDGALVVLWRPEGAAVANRIVARYVVGADGARSKVAALAVAGAAPPCVAA
YHEIIRAPAAPAASAPTPATAAGPAYDPARCDVIYRGDISPDFYGWIFPHGETLSIGSGT
AVKGFSLREAVALLRREAGLDGLEVVRREGAPIPLRPRKRWDNGRDVVLIGDAAGVVAPA
SGEGIYYAMASGKMAAEALGEALAGAGPAALAQVRRRFLKAHGKTFWSLGLLQRFWYRSD
RWRESFVAICADRDVQRLVWQSYLTKDLARGNMGAYMRIFFKDVAHLIGIAKS