Protein Info for Rru_A0619 in Rhodospirillum rubrum S1H

Annotation: Magnesium protoporphyrin O-methyltransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 TIGR02021: magnesium protoporphyrin O-methyltransferase" amino acids 10 to 230 (221 residues), 260.6 bits, see alignment E=5e-82 PF03602: Cons_hypoth95" amino acids 40 to 110 (71 residues), 32.6 bits, see alignment E=3.2e-11 PF13489: Methyltransf_23" amino acids 47 to 155 (109 residues), 39.5 bits, see alignment E=2.4e-13 PF05175: MTS" amino acids 48 to 156 (109 residues), 33 bits, see alignment E=2.3e-11 PF02353: CMAS" amino acids 61 to 140 (80 residues), 28.9 bits, see alignment E=3.6e-10 PF13847: Methyltransf_31" amino acids 61 to 162 (102 residues), 56.6 bits, see alignment E=1.2e-18 PF08241: Methyltransf_11" amino acids 66 to 150 (85 residues), 52.4 bits, see alignment E=3.5e-17 PF08242: Methyltransf_12" amino acids 66 to 153 (88 residues), 49.1 bits, see alignment E=3.9e-16 PF13649: Methyltransf_25" amino acids 66 to 153 (88 residues), 65.2 bits, see alignment E=3.7e-21 PF07109: Mg-por_mtran_C" amino acids 132 to 232 (101 residues), 115.2 bits, see alignment E=7.2e-37

Best Hits

Swiss-Prot: 56% identical to BCHM_RHOCA: Magnesium-protoporphyrin O-methyltransferase (bchM) from Rhodobacter capsulatus

KEGG orthology group: K03428, magnesium-protoporphyrin O-methyltransferase [EC: 2.1.1.11] (inferred from 100% identity to rru:Rru_A0619)

Predicted SEED Role

"Mg-protoporphyrin O-methyltransferase (EC 2.1.1.11)" in subsystem Chlorophyll Biosynthesis (EC 2.1.1.11)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RWS2 at UniProt or InterPro

Protein Sequence (236 amino acids)

>Rru_A0619 Magnesium protoporphyrin O-methyltransferase (NCBI) (Rhodospirillum rubrum S1H)
MPTMSYHTRRGQLETYFDRTAADAWKRLTSDAPVGKIRATVRAGRDSMRETLLSWLPDDL
SGTRLLDAGCGTGSFAVEAARRGASVVAIDISPTLIDLARERAAEVTGPGRIEFRVGDML
DPALGEFDHVVAMDSLIHYQAADTVQVLERLAARTSKTMVFTFAPRTPMLSVMHAVGKLF
PRGDRAPAIQPLGEKSFRWKIVGEAGLADWSLGRTQRVKCGFYISQALELVRACAD