Protein Info for Rru_A0520 in Rhodospirillum rubrum S1H

Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 transmembrane" amino acids 202 to 221 (20 residues), see Phobius details PF10090: HPTransfase" amino acids 101 to 215 (115 residues), 71 bits, see alignment E=3.8e-24

Best Hits

KEGG orthology group: K13588, histidine phosphotransferase ChpT (inferred from 100% identity to rru:Rru_A0520)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RX21 at UniProt or InterPro

Protein Sequence (224 amino acids)

>Rru_A0520 hypothetical protein (NCBI) (Rhodospirillum rubrum S1H)
MSETPFSPHSFAASAPSVPDRAEGAAEDLDLALMLCTRLCHDLAGSIGAVNTGAELLEEE
GEAFDPETLALLADSARGAALRLKVLRMAMGLVRGRQPTLAEAAEGLGGLLAASGRRFAL
GDPAMGDPGAPTVQLLVNLAMVAADVWPKAAEITLGATEDGYGVWARGAAGPPSASWDQA
LAGGDDVPDPRTVQAWLTKRLAARLGMAILIPSSQAGTLLLTRR