Protein Info for Rru_A0486 in Rhodospirillum rubrum S1H
Annotation: von Willebrand factor, type A (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K03404, magnesium chelatase subunit D [EC: 6.6.1.1] (inferred from 100% identity to rru:Rru_A0486)Predicted SEED Role
"Protoporphyrin IX Mg-chelatase subunit D (EC 6.6.1.1)" in subsystem Chlorophyll Biosynthesis (EC 6.6.1.1)
MetaCyc Pathways
- 3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent) (7/9 steps found)
- 3,8-divinyl-chlorophyllide a biosynthesis I (aerobic, light-dependent) (6/9 steps found)
- 3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic) (6/9 steps found)
- superpathway of bacteriochlorophyll a biosynthesis (13/26 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 6.6.1.1
Use Curated BLAST to search for 6.6.1.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RX54 at UniProt or InterPro
Protein Sequence (605 amino acids)
>Rru_A0486 von Willebrand factor, type A (NCBI) (Rhodospirillum rubrum S1H) MTAPAAFNPLTWDEAARAAAMVAVDPVGLGGAVIRALPGPPRDRWLAYLRELLPADAPLR RMPLHISDDRLLGGLDLAATLRAGRPVAQRGLLAEAHNGIVVLAMAERAPVGTVAQLCSV IDCGEVRTERDGLGLRSPAHLGVVALDEGLEEDEHPLASLVDRLAISLDLGPLRDLSDDG ELPDADMVQAARENLGAVTIPETLIETLCATAAAFGILSLRVPLFALRVARTAAALDGRT AVEDADIMTAVRLVLAPRALVLPMPPEDDAEDQPPPPPPPEEPPESEPEQKKDQDDQGGP TLEEMAVAAAAAIMPAGMLARLRAAGGLRRKVTPPGKAGALKAAKTRGRPAGTRPGAPGP GARLSVIDTLRAAAPWQRVRRDEEAARLGDEGVPPAEGGPAGPRVLVRPDDFRVTRLRQR AQTTTIFVVDASGSSALHRLAEAKGAVELLLADCYVRRDQVALVAFRGARADVLLPPTRS LVRAKRSLQRLPGGGGTPLASGLDAATALAELCQRRGETPVLVVLTDGRANVGRDGTGGR AKAEADAQSAARALRAMGLGVLLVDTAPRPDPRARKLAEELDACYLALPHADAMAISQGV RAAMT