Protein Info for Rru_A0438 in Rhodospirillum rubrum S1H

Annotation: Multi-sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 914 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 303 to 327 (25 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 5 to 99 (95 residues), 28.1 bits, see alignment E=4.2e-10 TIGR00229: PAS domain S-box protein" amino acids 385 to 501 (117 residues), 32.4 bits, see alignment E=4.4e-12 amino acids 508 to 629 (122 residues), 25.4 bits, see alignment E=6.3e-10 PF13426: PAS_9" amino acids 398 to 494 (97 residues), 28.4 bits, see alignment E=5.1e-10 PF02518: HATPase_c" amino acids 788 to 895 (108 residues), 90 bits, see alignment E=4.2e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0438)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXA2 at UniProt or InterPro

Protein Sequence (914 amino acids)

>Rru_A0438 Multi-sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MAWRLSVRMRLLAVFGVAALFAVIASAMGLLAFGSVERAQKSFLESRLPTVELAQSLAHR
AQAVAAAAPQMVIASTQAGRDSAGAQISTQIANLDRLLVALRPRVSDRSFLEQLEAQKAD
LTEALKALDHWVGRRIGLRRKLDERLSEARDRLNEARALLAHRLAKSSPADDQPVRLAMA
LVSIERAATLLEALPLAAAGRLAWLESAFGAELTMAARDSEGDGSWEGAGEVRGALAAAE
ALARGPEGLFATRDGLEEAERRCEALLVAYSQFANRLVYSADTLAAETAAVMNADGRSLT
ATLGLISLILLAIAALAVGGALVMALFADRTISGRLATLRQSMAAHVAGLDAPLPDLGRD
EIGEMAQALKIFVATIADREGALKASQDYLRAVLDAVPEGILTITDTGEVVGASRSAESL
FGPGPGLIGKELSLLISDAEGGRLSLEGAESAGAPQAVIAHRADGDSFPGEITVAGILRD
DRQIHVLSLRDISERQRIEAERQRFVALLAAAQEATADGLMVIDLDGAIITCNQKYYDTV
GISPDAFVPRSRDERLALLAGLMAEPQYFIDRIEEMEADPDLTAYDILHLADGRLIERYS
SPFKVGGILAGRLWSVRDITEREKARAELTEAKEAAERALSDLKDAQRNLVEAEKMAALG
QLVAGIAHEINTPVGITVTAASFIADEAKAIGALIDAGTLRRSRFAGFLESLRESSTLLL
SNANRAAELIQSFKQVAVDQTSDERRTFDLGHYVTEVLISLGPSLRKLPHRVTVDIPPGI
ILDSYPGALAQILANIVLNALSHAFLPQRAGQITVTARETEEEVVELRIADNGRGMSPEV
RDQVFEPFFTTTRGAGGSGLGLHIAYNLANRTLGGRIGVDSAPGEGTTFIVIIPRVAPPA
PRALRSSGTVIHGQ