Protein Info for Rru_A0433 in Rhodospirillum rubrum S1H

Annotation: PpiC-type peptidyl-prolyl cis-trans isomerase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 signal peptide" amino acids 1 to 54 (54 residues), see Phobius details PF09312: SurA_N" amino acids 58 to 167 (110 residues), 51.9 bits, see alignment E=1.7e-17 PF13616: Rotamase_3" amino acids 203 to 299 (97 residues), 54 bits, see alignment E=4.7e-18 PF00639: Rotamase" amino acids 210 to 298 (89 residues), 63.6 bits, see alignment E=5.6e-21

Best Hits

KEGG orthology group: K03771, peptidyl-prolyl cis-trans isomerase SurA [EC: 5.2.1.8] (inferred from 100% identity to rru:Rru_A0433)

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXA7 at UniProt or InterPro

Protein Sequence (444 amino acids)

>Rru_A0433 PpiC-type peptidyl-prolyl cis-trans isomerase (NCBI) (Rhodospirillum rubrum S1H)
MLNRMIAFRPLSQPAPGATPACTARALGRLLGIALLAWVAVLGCGWPVHTAQAAVPTQRI
AAVVNEDAVSLYDLNARIDIVMATGGMPNSPEVRQRLAPQILRALIDETLKIQEAKRANV
TVSTEDINGGIERLERQNKLPPGGLEKAFKAAGLDQQSLIHQIRAELGWIKAVQSTLGPR
VNVSEDEISLYQQNLQRNLGKPEYLVADIFLPVDNAAQDAEVLTAAQRMIEQMRLGANFA
ALAQQFSRGPAAQRGGDLGWVGPGEIDAEVLQALGAMAPGNLSQPIRTFGGYHILLLRDQ
RIASGGASSLLKMSRIVIPLRGPRMPTPERLADLRQRIAATRSCEAFDALAGEVGPPSGS
MGSIDPARLPAEAQNVIRDLPAGQPSTPLTMDNAEIRLMICDRPTGGLPGRDILRERLIE
QKLQNLAQRRLRDLRQQAIIDIRV