Protein Info for Rru_A0326 in Rhodospirillum rubrum S1H

Annotation: Transcriptional Regulator, NifA subfamily, Fis Family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 733 PF13185: GAF_2" amino acids 25 to 164 (140 residues), 32.9 bits, see alignment E=2.6e-11 amino acids 203 to 345 (143 residues), 32.2 bits, see alignment E=4.3e-11 PF01590: GAF" amino acids 203 to 344 (142 residues), 40.9 bits, see alignment E=1e-13 PF00158: Sigma54_activat" amino acids 387 to 553 (167 residues), 237 bits, see alignment E=3.3e-74 PF14532: Sigma54_activ_2" amino acids 388 to 558 (171 residues), 58.6 bits, see alignment E=3e-19 PF01078: Mg_chelatase" amino acids 400 to 536 (137 residues), 25.2 bits, see alignment E=3.5e-09 PF07728: AAA_5" amino acids 411 to 529 (119 residues), 28.8 bits, see alignment E=3.8e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0326)

Predicted SEED Role

"Formate hydrogenlyase transcriptional activator" in subsystem Formate hydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXL4 at UniProt or InterPro

Protein Sequence (733 amino acids)

>Rru_A0326 Transcriptional Regulator, NifA subfamily, Fis Family (NCBI) (Rhodospirillum rubrum S1H)
MGEAHSLAERYELLLDVSEILELNRDLNSLLGALCDLPASIGLFDYVNLLLYDAPTDTMT
LFSQGDVGGGYARIDGLAPTEGPGQVVWARQRPFVCSGEEYRRHFLKIAALRRNQRVGLY
CQMPLTTSQRRLGGVEFISSRPTTYDEDDLTFLRRVASVIAISVENALIGEMRQMEEERL
RGERDHNHILVEVTNAVISKLKLEDLVDEVSRSIHRFFGVDFVSLDLVDPATATIKSRSV
YFQKGLGPVWGSAQGPLGASPMAPLFETKAPRILARADLGALARGHDQMTLLTNAGFQVA
CGIPLLSAGHVLGVLTLASRERDKFTDYNIGLLGEVASRICIAVENALAYGEISRLKDQL
SRENKQLAKERYYLEEEIRRTEDFGDIIGISPAIRGVLEQVELVADSDSTVLILGETGTG
KELIARAIHMLSQRKKRTMIKVNCAAIPSALLESDLFGHEKGAFTGAIAQKSGRFELADR
GTLFLDEVGDIPIDLQPKLLRALQEREIERVGGHQPIPVDVRMIAATNRDLTGMVEKRLF
RGDLYYRLNVFPILIPPLRERREDIPLMADYFMRKTARKMNRAIEAFSAETMDMLLNLPW
PGNVRELQNVIERAVILTKGPVLHLPATELRHHLAPSAALPSEDAVIPLRAAVLPSAASA
PDPLPPPAGSSPNPGDLAGEAIERDQILRVLRETNGIVGGPRGAAAHLGMKRTTLLSRMR
RLGISPKEVDHRA