Protein Info for Rru_A0242 in Rhodospirillum rubrum S1H

Annotation: Type III restriction enzyme, res subunit (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1014 PF04851: ResIII" amino acids 169 to 350 (182 residues), 33.4 bits, see alignment E=2.1e-12

Best Hits

KEGG orthology group: K01156, type III restriction enzyme [EC: 3.1.21.5] (inferred from 100% identity to rru:Rru_A0242)

Predicted SEED Role

"Type III restriction-modification enzyme, helicase subunit"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.21.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXU8 at UniProt or InterPro

Protein Sequence (1014 amino acids)

>Rru_A0242 Type III restriction enzyme, res subunit (NCBI) (Rhodospirillum rubrum S1H)
MSEAFFDRPILNSPYEYPSQHWELDAEGQPTNKIIGSRRRSDLITPVPKPKKRKKPKTPK
EQSGFVFDSGDGLSTAEQEYNPTPIINEIRQHVGSWRSLPNPSDWLVTPETARLLQHWRH
HTFHGVRPFFCQVEAVETAIWLTEVAPKLGKKGERFWDHIKGANEQANPELLRLALKLAT
GAGKTTVMAMLIAWQTVNAVRHPNSKTFSRGFLLVAPGITIRDRLRVLLPNDPESYYRNR
ELVPADMLADTERAKIVITNYHAFKLRERLEISKVGRALLRGRGPELNTLETEGQMIQRV
MPDLMGLKNIVVLNDEAHHCYREKPQNDDLDDLKGEDKEEAKKNNEAARMWISGLEMVKR
TLGLRAIFDLSATPFFLRGSGYAEGTLFPWTVSDFSLMDAIECGIVKLPRVPVAQNAPGD
TLVFRNLWDHIGKKMPKAGRSGGKFLDPLSLPAELQTALYALYGHYEKTYDLWQQERVEV
PPVFIVVCNNTSTSKLVYDFISGFYRPGGQEGASFLENGRLALFRNYDDHGNHLPTPRTL
LIDSEQLESGDALDKEFRASAADEIERFRRDIRQRTGDIKRAENITDQDLLREVMNTVGK
KGKLGEQVRCVVSVSMLTEGWDTNTVTHVLGVRAFGTQLLCEQVIGRALRRQNYELNEET
GLFNVEYADVLGVPFDFNAKPVVAPPVKPRETVRVQAVRPDRDALEITFPRVEGYRVELP
DERLVATFTQDSVLDLTPDLVGPSITTNQGIIGQDVDLTIGHLNNMRQSTILFHLTKHLL
YSKFRDPGDEPKLHLFGELKRITRQWLDDGYLRCSGGTFPAQLVYQGIADMAAERIKAAI
TLSLVGYHPVKAILDAYNPTGTTATVNFTTSKPLRWKTDAGRCPINWIVCDSDWEAEFCR
VAERHPLVRAYVKNHGLGFEVPYLFGSIPRRYLPDFIVQVNDGRTDPLNLIVEIKGFRGE
DAKDKANTMHAYWVPGVNNLGKFGRWAFAEFTAVYEIEAKFNELIASVVADQAA