Protein Info for Rru_A0241 in Rhodospirillum rubrum S1H

Annotation: DNA methylase N-4/N-6 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 939 PF01555: N6_N4_Mtase" amino acids 154 to 485 (332 residues), 119.5 bits, see alignment E=1.1e-38

Best Hits

KEGG orthology group: K00571, site-specific DNA-methyltransferase (adenine-specific) [EC: 2.1.1.72] (inferred from 100% identity to rru:Rru_A0241)

Predicted SEED Role

"Adenine specific DNA methylase (Mod-related)"

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXU9 at UniProt or InterPro

Protein Sequence (939 amino acids)

>Rru_A0241 DNA methylase N-4/N-6 (NCBI) (Rhodospirillum rubrum S1H)
MAKEIGVETLTHKDAKRVNIPTAELQSVMQEEVKSPIRVAYDRRNRDLDPQLVWRGKDER
DWSELIVQAPPLYIQEKIHPKVLIDDLKRESRARAKEMVGATVDLFADFNGLPDKEAATE
FYQHHANWTNRMILGDSLSVMASLAEREGLRGKVQCIYFDPPYGIKFNSNFQWSTTSRDV
KDGNKDHITREPEQVRAFRDTWRDGIHTYLSYLRDRLTVARDLLTDSGSIFVQIGDENVH
RVRMLMDEVFGDENFISQISTKTSGGSTGEYISNVVDFILWYSKSRSYIKFRKLNKSKEI
GEAGSEKYTRIRFDNLHSRALTPEERLSTSSVPCDGRVYRQDNMTSQSVGRDKGEGAASW
FPVIISGSEIKPSLRVRWKTNQTGMDRLLKAERLELTGNSISYVRFIDDFSGIPLSNSWD
DIGGIQSRLDPKVYVVQTPTTVIQRCILMASDPGDLVLDPTCGSGSTAFVAEQWGRRWIT
IDTSRVSLALARARIMGARYPYYLLADSRDGQVKEGQVTRTLPKDTPTHGDIRQGFVYER
VPHVMLSNIASNSEIDVIWDKAQETLEPLRTQLNAALDKTWHDWEIPREADKGWSAAAKA
LHAQWWDARIRRQKEIDASIAAKAEFEYLYDKPYEDKAKVRVAGPFTVESLSPHRVLAVD
QNDELVDLLQAAEGKGASKSLDASDFAQMVLDNLKSAGVQQAHKEDRIAFTALTGWPGKF
ICAKGVFREGDKDRSAGIVIGPEFGTVSRLDLVTAAREAGDAGFDVLIACAFNFDAHSAE
FDKLGAIRILKARMNPDLHMGGDLKSTGAGNLFVVFGEPDIDIIITADDKVRVKIKGVDI
FHPSTGEIESGGPDTIAVWFIDTDYNEESFFVRHAYFLGADDPYKALKTTLKAEIDREAW
DSLNRDISRPFDKPKSGRIAVKVINHLGDEVMKVFSVDV