Protein Info for Rru_A0124 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate phosphodiesterase (EAL domain) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 PF00563: EAL" amino acids 228 to 390 (163 residues), 32.1 bits, see alignment E=3.9e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0124)

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RY66 at UniProt or InterPro

Protein Sequence (449 amino acids)

>Rru_A0124 Putative diguanylate phosphodiesterase (EAL domain) (NCBI) (Rhodospirillum rubrum S1H)
MPQSTVVSGGARAMMEMLGRLEAAPAGYQVAVIALSQLQPEFRRPLLVRRATDLFEPLVK
AVGGPRVYLPDSLDIVVIGKNLSRAGVRLAAEGIRTLFGADPLVRGRTGGGIDRFARWFD
LGRADHHGAFKALADDIDRRSAEQAQATGAWDGHEQPLTPKRLALLISDMETLDVAPLLQ
RQPVIRVTKAPSAEIDFEEIFISLSALRKRVAEHIDLQSDRWLFQDFSRSLDRHILRTLK
PLATCRGAGTISVNLNLETLTSDTFEGFVQAMPLEQRLIVEVQGIDVFADIGAFLRARDR
LRNRGHRLLIDGLTPRTMETVDLGQLDADFYKLQWNPGFIHVVDGDEAAAARGLIGAIGA
AKLVLSRVESEQAMTWGLLCGIRRFQGFFVDTLLGGAILGACHDPGHCTLSRCIATRRGV
SGLLREQCRDRAALDHTVRIAGRAKRIAS