Protein Info for Rru_A0099 in Rhodospirillum rubrum S1H

Annotation: Serine phosphatase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 663 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 292 to 314 (23 residues), see Phobius details PF00672: HAMP" amino acids 314 to 360 (47 residues), 29.5 bits, see alignment 7.7e-11 PF07228: SpoIIE" amino acids 463 to 661 (199 residues), 116.5 bits, see alignment E=1.5e-37

Best Hits

KEGG orthology group: K07315, sigma-B regulation protein RsbU (phosphoserine phosphatase) (inferred from 100% identity to rru:Rru_A0099)

Predicted SEED Role

"Serine phosphatase RsbU, regulator of sigma subunit" in subsystem SigmaB stress responce regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RY91 at UniProt or InterPro

Protein Sequence (663 amino acids)

>Rru_A0099 Serine phosphatase (NCBI) (Rhodospirillum rubrum S1H)
MILTRALRKMPLGRRLMLTMAIYALAVLVIVVSGWRLVTLVEDYRSTTEVLDLRMREITA
VRDTSSRFLTVITAYADTRDPAIGDDVAFKYGQIGRAAEAVSLKEDDIEAVLGGLETVLK
DSMGNFEDLRALNQRAGQTYHHLGRLAGEVSGLMAFAQSRMAQAGGSPDPLIARFDQVTA
LIDEFHIFQRRATGKEAESTLAAFRDALESASRSRPTEAERLALSLADDRLGQISHELTT
LLRLSDSWVGQSRFLVFVNLEKVTAAIDALDTLGKVREHQLRADLQDKTRATLIFVGSLA
GVVLVLGFLANALVIQSIRRPILALNEVMQNLAGGTLDRAVEGQEAADEIGAMARTLEIF
KLNTRRMNELEVEKREILRRENEEIAQSLAQLDEAHREISALNTRLNSENLRLGAELDVS
RRIQQMLLPRDEELSEITALDIAAFMESADEVGGDYYDIMKHEGGVRIGIGDVTGHGLES
GVVMLLTQSAVRTLTTDGRGDRASLVDVLNRSLAGNMRRMGSGKNLTFALIDYQPRPEGG
GAMRVIGQHESLIVIRTDGRVEELDTLMLGMPLGLVDDMRTYLDEAALSLEPGDMVVLYT
DGITEAADTGDRLYGMDRLKATCLAHRTETSGAIKDAVIADVRAHIGERAVLDDLTLIVI
KQR