Protein Info for Rru_A0065 in Rhodospirillum rubrum S1H

Annotation: Squalene/phytoene synthase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 TIGR03464: squalene synthase HpnC" amino acids 23 to 286 (264 residues), 310.4 bits, see alignment E=5.5e-97 PF00494: SQS_PSY" amino acids 26 to 275 (250 residues), 178.6 bits, see alignment E=1.1e-56

Best Hits

Swiss-Prot: 44% identical to HPNC_RHOPA: Hydroxysqualene synthase (hpnC) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0065)

MetaCyc: 44% identical to hydroxysqualene synthase (Rhodopseudomonas palustris CGA009)
RXN-17129 [EC: 4.2.3.156]

Predicted SEED Role

No annotation

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.3.156

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RYC5 at UniProt or InterPro

Protein Sequence (297 amino acids)

>Rru_A0065 Squalene/phytoene synthase (NCBI) (Rhodospirillum rubrum S1H)
MAAPDTPPDSPPPISAVEMPSGKDAGTENFPVGSVLLPARLRPHVARFYAFARAIDDIAD
SPDLDAAAKIDRLQGFEEAITGRDTTDPAYAKGHALRVSLEATGVPAIHGVELIAAFKQD
AVKGRYATWAEMMDYCRLSAAPVGRYLIDLHGGSRAGYASSDALCVALQVINHLQDCQDD
FRVLDRVYLPADWLAAEGASVSDLDRAACTPGLRRVLDRCLEGTRRLLDAARPLPGDIID
RRLGLEAAVIVSIAQTLTGRLARQDPLAQRVKLGKAATAFCAARACAAYLMVPGAYR