Protein Info for Rru_A0024 in Rhodospirillum rubrum S1H

Annotation: peptidase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF13365: Trypsin_2" amino acids 114 to 249 (136 residues), 113.8 bits, see alignment E=3e-36 PF00089: Trypsin" amino acids 115 to 272 (158 residues), 66.1 bits, see alignment E=1.1e-21 PF00595: PDZ" amino acids 284 to 367 (84 residues), 42.8 bits, see alignment E=1.4e-14 PF13180: PDZ_2" amino acids 288 to 374 (87 residues), 48.7 bits, see alignment E=1.9e-16 PF17820: PDZ_6" amino acids 314 to 368 (55 residues), 34.4 bits, see alignment 3.8e-12

Best Hits

Swiss-Prot: 43% identical to Y938_SYNP6: Uncharacterized serine protease syc0938_d (syc0938_d) from Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 100% identity to rru:Rru_A0024)

Predicted SEED Role

"HtrA protease/chaperone protein / Serine protease (Protease DO) (EC 3.4.21.-)" (EC 3.4.21.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RYG6 at UniProt or InterPro

Protein Sequence (381 amino acids)

>Rru_A0024 peptidase (NCBI) (Rhodospirillum rubrum S1H)
MTRRRCGVWSMLGGAALVLSTIGPAGALPPAPAAAGAGLGPSLALTPVFMVGEEGVLTLA
PTLEIVTPAVVNIAVKATVAARPNPLLSDPLFRQFFGVPPGAEGPRERTVVSAGSGVIVD
AVRGTILTNHHVVDGAEDITVTLKDRRVLKATLLGSDPGTDIAVLRVKADRLTALHLADS
DRAQVGDLTIAIGNPFGLGQTVTTGVISAKGRSGVIPDGYEDFLQTDASINPGNSGGALV
NSRGDLVGINTAILSSGGGSVGIGFAIPSNIARAVMEQILKDGTVRRGHLGVSIQTVSPA
VAESLGLPRAAGVIIAAVERGSTAEKVGLRTGDVILAVDGRPSETAEVLRRQIGLAQIGD
RVRLTVMREGKSFDLQARIGS