Protein Info for Rru_A0014 in Rhodospirillum rubrum S1H

Annotation: KpsF/GutQ (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 PF01380: SIS" amino acids 89 to 217 (129 residues), 95.5 bits, see alignment E=2.4e-31 TIGR00393: sugar isomerase, KpsF/GutQ family" amino acids 90 to 356 (267 residues), 301.2 bits, see alignment E=3.8e-94 PF00571: CBS" amino acids 254 to 301 (48 residues), 26.9 bits, see alignment 4.9e-10 amino acids 311 to 363 (53 residues), 29.4 bits, see alignment 8.4e-11

Best Hits

Swiss-Prot: 53% identical to KDSD_PSEAE: Arabinose 5-phosphate isomerase KdsD (kdsD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K06041, arabinose-5-phosphate isomerase [EC: 5.3.1.13] (inferred from 100% identity to rru:Rru_A0014)

MetaCyc: 50% identical to D-arabinose 5-phosphate isomerase KdsD (Escherichia coli K-12 substr. MG1655)
Arabinose-5-phosphate isomerase. [EC: 5.3.1.13]

Predicted SEED Role

"Arabinose 5-phosphate isomerase (EC 5.3.1.13)" in subsystem KDO2-Lipid A biosynthesis (EC 5.3.1.13)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RYH6 at UniProt or InterPro

Protein Sequence (366 amino acids)

>Rru_A0014 KpsF/GutQ (NCBI) (Rhodospirillum rubrum S1H)
MTERKTGSPFSARRSRLGFEEGNGFAMTIPSPSISAPVADLSDEAGRALACARHVLEAEA
EALRALAADLNGAFTAAIDLLCDGPAKRSGKVIISGMGKSGHVAAKIAATLASTGTPSFF
VHPAEASHGDLGMIGRSDAVIALSNSGETPELADMVAYTRRMGIPLISITGRHPSALSDA
ADVALVLPALTEACPHGLAPTTSTTAMMALGDALAVALLERRGFTASDFRLFHPGGQLGR
KLLKVADLMHGQDRLPLVGPATPMAEAILEISSKSLGCVGVVDAAGRLAGIITDGDLRRH
MGADLWSRTAGSVMTPTPKTIAPTTLAIEGLRIMNESAITGLFALDADKRPVGFLHLHDC
LRAGLA