Protein Info for Rru_B0037 in Rhodospirillum rubrum S1H

Annotation: Hemolysin-type calcium-binding region (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 830 PF00353: HemolysinCabind" amino acids 182 to 194 (13 residues), 7.3 bits, see alignment (E = 0.00025) amino acids 629 to 653 (25 residues), 22.6 bits, see alignment (E = 4.3e-09) amino acids 647 to 674 (28 residues), 22.3 bits, see alignment (E = 5.4e-09)

Best Hits

Predicted SEED Role

"Alkaline phosphatase (EC 3.1.3.1)" in subsystem Phosphate metabolism (EC 3.1.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.1

Use Curated BLAST to search for 3.1.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RML2 at UniProt or InterPro

Protein Sequence (830 amino acids)

>Rru_B0037 Hemolysin-type calcium-binding region (NCBI) (Rhodospirillum rubrum S1H)
MSLAFNATYYLTAYPDVAKAVSLGQFASAEAHYNLFGAKELRNPNSYFDANYYAAQNPDV
LNAVSNGAFPSVWAHFLAYGAAEERAPSTALAAFNETSYLAANPDVAAAVTAGSMPSALY
HFLAFGVDEGRSGSGVTIGENVGQTYTLTTGVDALTGTANNDTFNGYVNVTANSTNSTFT
ASDSIDGGAGKDSLHITVEGNAAGSLPAATITSVENFFVREVGGTAGSYDFGTVLGEEQV
WSDRSTDAVTFANLAAGTTVGLKGDGATVLGNVTFEQVTAAAAVNIAIDGVGTTGAPTIT
NGVAANAITTNPTVATITSTGVANTVGAIDLTETAGSATAGIATLNINAETNLTATLVAA
DFNTTGAALKVAGLASSVDVGSLGVFKTIDASGLTAGGVTVGLNAVTTSFAGGAGNDVVT
TAALAATVAASAINAGAGTADRLVVNATTDVDTAAEAQHYAGFEVLQVGAGVTADASLFT
NSAINAVRFTGSGTINGLNATQAANVTVTANATPVIGITGASDVGQIDTVKITADDGAAA
VSTITLANVNAAGVENLQFVATDAITVSSLTSSAAVTGITVTGAHDVSITTGALGVNVNT
AIDASALTGAFTLDASAATGANGLSVTSGTGNDTITGTANADIIRVGAGNDTVTAGAGID
RIDLGAGNDTVVFGEAFAAGNANHDVVTGFTFGAASEDKYDIGFTVANGTTNATANLAAL
APVAVADNGSASANDVIFTFSGANDKLAANTTATTAVANAVTALTSGGDFAASNVTAGDS
LVLVLDNGTDSFIFHYVADATPATTSAADLELIGVVTGQLASQVVTGDFI