Protein Info for Xcc-8004.616.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 538 TIGR00497: type I restriction-modification system, M subunit" amino acids 7 to 514 (508 residues), 384.2 bits, see alignment E=4.9e-119 PF12161: HsdM_N" amino acids 9 to 170 (162 residues), 85.9 bits, see alignment E=4.2e-28 PF02384: N6_Mtase" amino acids 179 to 500 (322 residues), 356.6 bits, see alignment E=1.3e-110

Best Hits

KEGG orthology group: K03427, type I restriction enzyme M protein [EC: 2.1.1.72] (inferred from 100% identity to xcc:XCC0466)

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X4U9 at UniProt or InterPro

Protein Sequence (538 amino acids)

>Xcc-8004.616.1 Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72) (Xanthomonas campestris pv. campestris strain 8004)
MTKDDQKELGKTLWAIADQLRGSMNADDFRDYMLSFLFLRYLSDNYEAAAKKELGSDYPD
AKTIGNSDKTPLSVWYASNPGDVAAFEQQMRRKAHYVIKPKYLWGNIVNLAKKQNHDLLD
TLQQGFKHIEEDSFESEFQGLFSEINLASDKLGRKYDDRNAKLCSIISEIARGMALSAKT
DSLGDAYEYLIGQFAAGSGKKAGEFYTPQEISNILSAIVTLDSQEPKTGPRGKLDSVFDF
ACGSGSLLLNIRNRMTNSGGSIGKIYGQEYNVTTYNLARMNMLLHGVKDTEFEIYHGDTL
KNDWDWLRETNPAKKPRFDAVVANPPFSYRWEPGEAMAQDARFKNHGVAPKSAADFAFLL
HGLQYLKDDGVMAIILPHGVLFRGGKEADIRRKLLDDGHIDTVIGLPANLFYSTGIPVCI
LVLKKCKKPDDVLFINAAGHFAKGKRQNQLTDEHIQRIVNTYQNRNKQDRYSRCVSMKEI
ADKDYNLNISRYVSTAEADKEIVLEAVHADLTAIESRLEESKKRHNAFLVELGLKPLP