Protein Info for Xcc-8004.5105.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: DNA polymerase I (EC 2.7.7.7)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 927 PF02739: 5_3_exonuc_N" amino acids 3 to 165 (163 residues), 176.4 bits, see alignment E=7.7e-56 TIGR00593: DNA polymerase I" amino acids 4 to 927 (924 residues), 895.3 bits, see alignment E=2.8e-273 PF01367: 5_3_exonuc" amino acids 166 to 260 (95 residues), 103.1 bits, see alignment E=2.1e-33 PF01612: DNA_pol_A_exo1" amino acids 329 to 515 (187 residues), 116.5 bits, see alignment E=2.4e-37 PF00476: DNA_pol_A" amino acids 550 to 925 (376 residues), 518.7 bits, see alignment E=1.8e-159

Best Hits

KEGG orthology group: K02335, DNA polymerase I [EC: 2.7.7.7] (inferred from 100% identity to xcb:XC_4109)

Predicted SEED Role

"DNA polymerase I (EC 2.7.7.7)" in subsystem DNA-replication or DNA Repair Base Excision (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2XC44 at UniProt or InterPro

Protein Sequence (927 amino acids)

>Xcc-8004.5105.1 DNA polymerase I (EC 2.7.7.7) (Xanthomonas campestris pv. campestris strain 8004)
MSRLVLIDGSSYLYRAFHALPPLTNAQGEPTGALFGVVNMLRATLKERPAYVAFVVDAPG
KTFRDDLYADYKANRPSMPDDLRAQVQPMCDIVHALGIDILRIDGVEADDVIGTLALQGA
SDGLAVTISTGDKDFAQLVRPGVELVNTMSGSRMDSDEAVIAKFGVRPNQIVDLLALMGD
TVDNVPGVEKCGPKTAAKWLAEYDSLDGVIANADKIKGKIGENLRAALPRLPLNRELVTI
KTDVVLASGPRALDLREPNAEALAVLYARYGFTQALRELGGAAAEAGGLTAPMAVARTEP
GRARGTGFVSAPAAAPVELDPALSAPGQYETILTQAQLDSWIARLRAAGQFAFDTETDSL
DALQANLIGLSVAAEPGQAAYLPFGHDFPGAPAQLDRTQALAQLAPLLTDPAVRKLGQHG
KYDLHVMRRHGIALAGYADDTLLESFVLNSGSARHDMDSLAKRYLGYDTVKYEDICGKGA
KQIKFAQVSLEDATRYAAEDADITLRLHQVLGKRLAAEPALESVYRDIEMPLVGVLERIE
ANGVCVDAAELRRQSADLSKRMLAAQQKATELAGRTFNLDSPKQLQALLFDELKLPAVVK
TPKGQPSTNEEALEAIADQHELPRVILDYRSLAKLRSTYTDKLPEMIHPQSGRVHTSYHQ
AGAATGRLSSSDPNLQNIPIRTEDGRRIRRAFVAPAGRKLIACDYSQIELRIMAHLSGDP
GLVGAFESGADVHRATAAEVFGRTIDTVSGDERRAAKAINFGLMYGMSAFGLARQLGIGR
GEAQDYIALYFSRYPGVRDFMETTRQQARDKGYVETVFGRRLYLDFINAGSQGQRAGAER
AAINAPMQGTAADIIKRAMVSVDGWIADHAQRALMILQVHDELVFEADADFVDTLLAEVT
ARMSAAASLRVPLVVDSGVGDNWDEAH