Protein Info for Xcc-8004.4560.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Histidine kinase/response regulator hybrid protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 475 PF00072: Response_reg" amino acids 32 to 146 (115 residues), 70.2 bits, see alignment E=4.2e-23 PF00158: Sigma54_activat" amino acids 185 to 348 (164 residues), 217.1 bits, see alignment E=3.2e-68 PF14532: Sigma54_activ_2" amino acids 198 to 353 (156 residues), 67.1 bits, see alignment E=4.9e-22 PF07728: AAA_5" amino acids 205 to 323 (119 residues), 23.1 bits, see alignment E=1.7e-08 PF02954: HTH_8" amino acids 435 to 470 (36 residues), 42.6 bits, see alignment 9.9e-15

Best Hits

KEGG orthology group: None (inferred from 99% identity to xca:xccb100_3787)

Predicted SEED Role

"Histidine kinase/response regulator hybrid protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2XBC4 at UniProt or InterPro

Protein Sequence (475 amino acids)

>Xcc-8004.4560.1 Histidine kinase/response regulator hybrid protein (Xanthomonas campestris pv. campestris strain 8004)
MPPMACGKAGWRRMLRSLTRTTSLQETAMPQILIIDDNSAVAMALEVLFSLHDIESRHAH
APQAGLDLLEEQQFDLVIQDMNFTADTTSGEEGEALFAQIRQRHPDLPVILLTAWTHLGS
AVGLVKAGAADYIAKPWDDTKLLTTVNNLLELSETRRELERRRNRERRGREQLAERYDLR
GAVFADPASERAIALACQVARSDLPVLITGPNGSGKEKIAEIIQANSAVKRGPFVALNCG
ALPGELIEAELFGAEAGAYTGANKAREGKFEAADGGTLFLDEIGNLPLAGQMKLLRVLET
GRYERLGSNRERHAKVRVISATNADLPAMIRDGSFREDLYYRLNTVEIALPALAERPGDI
APLAEHFLAGETLLSPQARDALQRHSWPGNVRELRNVLQRATLLAQGVRIEATDLNLPRS
ATARPAPLPGGEPDRARIEQALARAQGVIAQAAADLGLSRQALYRRMDRYGISQD